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Key Documents

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47628

Sigma-Aldrich

Fmoc-Ile-OH

≥98.0% (T)

Sinónimos:

N-(9-Fluorenylmethoxycarbonyl)-L-isoleucine, Fmoc-L-isoleucine

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About This Item

Fórmula empírica (notación de Hill):
C21H23NO4
Número de CAS:
71989-23-6
Peso molecular:
353.41
Beilstein/REAXYS Number:
4716717
EC Number:
276-255-9
MDL number:
MFCD00037125
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
57651048
NACRES:
NA.26

Quality Level

100

assay

≥98.0% (T)

form

solid

optical activity

[α]20/D −12±1°, c = 1% in DMF

reaction suitability

reaction type: C-H Activation
reaction type: Fmoc solid-phase peptide synthesis
reagent type: ligand
reaction type: Peptide Synthesis

mp

145-147 °C (lit.)

application(s)

peptide synthesis

functional group

Fmoc
amine
carboxylic acid

storage temp.

2-8°C

SMILES string

CC[C@H](C)[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C21H23NO4/c1-3-13(2)19(20(23)24)22-21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,3,12H2,1-2H3,(H,22,25)(H,23,24)/t13-,19-/m0/s1

InChI key

QXVFEIPAZSXRGM-DJJJIMSYSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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The clearance of host cell proteins (HCPs) is of crucial importance in biomanufacturing, given their diversity in composition, structure, abundance, and occasional structural homology with the product. The current approach to HCP clearance in the manufacturing of monoclonal antibodies (mAbs)
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European journal of medicinal chemistry, 44(5), 1933-1940 (2008-12-27)
Twenty-four new dipeptide analogs (1-24) of aurantiamide acetate were designed, synthesized, and assayed for effects on superoxide anion generation and elastase release by human neutrophils in response to fMLP/CB. Among them, seven N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides (6, 9, 12, 14, 17, 18
Yu-I Hsu et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 108(4), 1274-1280 (2019-08-21)
We recently reported a novel method to modify the polylactic acid (PLLA) nanofiber scaffold with IKVAV peptide/oligo (d-lactic acid) (ODLA) heteroconjugates. However, a part of the IKVAV sequence was not exposed to the outermost surface and therefore, cell adhesion was
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