409510
Poly(ethylene glycol) dimethacrylate
average MN 550, cross-linking reagent polymerization reactions, methacrylate, 80-120 ppm MEHQ as inhibitor, 270-330 ppm BHT as inhibitor
Sinónimos:
Polyethylene glycol, PEG dimethacrylate
About This Item
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product name
Poly(ethylene glycol) dimethacrylate, average Mn 550, contains 80-120 ppm MEHQ as inhibitor, 270-330 ppm BHT as inhibitor
form
liquid
mol wt
average Mn 550
contains
270-330 ppm BHT as inhibitor
80-120 ppm MEHQ as inhibitor
reaction suitability
reagent type: cross-linking reagent
reaction type: Polymerization Reactions
refractive index
n20/D 1.466
bp
>200 °C/2 mmHg (lit.)
density
1.099 g/mL at 25 °C
Ω-end
methacrylate
α-end
methacrylate
polymer architecture
shape: linear
functionality: homobifunctional
storage temp.
2-8°C
SMILES string
OCCO.CC(=C)C(O)=O
InChI
1S/C10H14O4/c1-7(2)9(11)13-5-6-14-10(12)8(3)4/h1,3,5-6H2,2,4H3
InChI key
STVZJERGLQHEKB-UHFFFAOYSA-N
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Application
- PDGF-AA loaded photo-crosslinked chitosan-based hydrogel for promoting wound healing.: This study investigates the use of a chitosan-based hydrogel, photo-crosslinked with Poly(ethylene glycol) dimethacrylate (PEGDMA), to deliver PDGF-AA and enhance wound healing. The results demonstrate significant improvements in wound closure rates and tissue regeneration (Cai et al., 2024).
- Reducing the foreign body response on human cochlear implants and their materials in vivo with photografted zwitterionic hydrogel coatings.: This research explores the application of PEGDMA in zwitterionic hydrogel coatings to minimize foreign body responses in cochlear implants. The coatings significantly reduced inflammation and improved biocompatibility in vivo (Horne et al., 2023).
- Full factorial design of experiment-based and response surface methodology approach for evaluating variation in uniaxial compressive mechanical properties, and biocompatibility of photocurable PEGDMA-based scaffolds.: This study uses a full factorial design to optimize the mechanical properties and biocompatibility of PEGDMA-based scaffolds, highlighting their potential use in tissue engineering and regenerative medicine (Bharadwaz et al., 2023).
- Antifouling and Mechanical Properties of Photografted Zwitterionic Hydrogel Thin-Film Coatings Depend on the Cross-Link Density.: This article examines how varying the cross-link density in PEGDMA-based hydrogel coatings affects their antifouling and mechanical properties. The findings are relevant for the development of durable and biocompatible medical device coatings (Jensen et al., 2021).
- Biocompatible and photocrosslinkable poly(ethylene glycol)/keratin biocomposite hydrogels.: The research presents the development of PEGDMA/keratin biocomposite hydrogels, demonstrating excellent biocompatibility and potential applications in drug delivery systems and tissue engineering (Wang et al., 2021).
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificados de análisis (COA)
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Artículos
Scaffold patterning with poly(ethylene glycol)-based hydrogels for cell presence in 2D and 3D environments on photoactive substrates.
Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.
Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.
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