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MilliporeSigma

374334

Sigma-Aldrich

1,1,1,2-Tetrafluoroethane

≥99%

Sinónimos:

HFC-134a

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About This Item

Fórmula lineal:
FCH2CF3
Número de CAS:
Peso molecular:
102.03
EC Number:
MDL number:
UNSPSC Code:
12142100
PubChem Substance ID:
NACRES:
NA.22

assay

≥99%

bp

−26.5 °C (lit.)

functional group

fluoro

SMILES string

FCC(F)(F)F

InChI

1S/C2H2F4/c3-1-2(4,5)6/h1H2

InChI key

LVGUZGTVOIAKKC-UHFFFAOYSA-N

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General description

1,1,1,2-Tetrafluoroethane is used as a trifluorovinylating agent in organic synthesis. It is identified as a potential refrigerant used in place of chlorofluorocarbons. 1,1,1,2-Tetrafluoroethane can also be used as a solvent and medical propellant for a wide range of applications. It is used to extract materials of natural origin like natural flavors, fragrances, and nutraceuticals.[1][2]

Application

1,1,1,2-Tetrafluoroethane can be used:
  • As a solvent in the preparation of cross-linked polymer microspheres through the dispersion polymerization method.[3]
  • As a porogenic solvent in the preparation of porous polymethacrylate monolith via free radical polymerization.[4]
  • In the synthesis of trifluorovinyllithium, a key intermediate for the preparation of 2-halo-2,3-dideoxy-arabinose derivatives of biological importance.[5]

Packaging

Supplied in a Sure/Pac cylinder and has a brass needle valve with a male 1/4" NPTF outlet thread installed. Before using the cylinder, ensure that the valve is closed, then remove the galvanized steel hex cap that seals the outlet valve.

Compatible with the following:

Legal Information

Aldrich is a registered trademark of Sigma-Aldrich Co. LLC
Sure/Pac is a trademark of Sigma-Aldrich Co. LLC

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hose barb

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regulator

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pictograms

Gas cylinder

signalword

Warning

hcodes

Hazard Classifications

Press. Gas Compr. Gas

Storage Class

2A - Gases

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Rebeca Weisleder et al.
Journal of the American Dental Association (1939), 140(8), 1013-1017 (2009-08-06)
In this article, the authors report on an in vivo study in which they assessed the validity of two commonly used cold pulp tests (carbon dioxide [CO(2)]and 1,1,1,2-tetrafluoroethane) and an electrical pulp tester (EPT) in determining pulp vitality by using
Sara Gunnare et al.
Toxicology letters, 167(1), 54-65 (2006-10-13)
The aim of this study was to determine the uptake and disposition of inhaled 1,1,1,2-tetrafluoroethane (HFC-134a) in humans. Ten male volunteers were exposed to 500 ppm HFC-134a (2 h, 50 W exercise). The HFC-134a levels were monitored in blood, exhaled
A simple stereoselective synthesis of biologically important 2-halo-2, 3-dideoxy-arabinose derivatives from 1, 1, 1, 2-tetrafluoroethane (134a) and 1-chloro-2, 2, 2-trifluoroethane (133a)
Coe PL, et al.
Journal of Fluorine Chemistry, 102(1-2), 43-50 (2000)
Anna Taddio et al.
Vaccine, 28(32), 5365-5369 (2010-05-21)
Although immunization injections are the most common painful medical procedures, pain-relieving interventions are not routinely used. In this randomized controlled trial, we compared the effectiveness of topical anesthesia using liposomal lidocaine to: (1) vapocoolant spray using a proprietary blend of
1,1,1,2-Tetrafluoroethane
e-EROS Encyclopedia of Reagents for Organic Synthesis. (2005)

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