Saltar al contenido
MilliporeSigma

258385

Sigma-Aldrich

Protoporphyrin IX disodium salt

≥90% (HPLC)

Sinónimos:

3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acid disodium salt, Depocolin-S, Ooporphyrin disodium salt

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización

Seleccione un Tamaño

250 MG
$51.20
1 G
$182.00
5 G
$567.00

$51.20


Disponible para envío el14 de abril de 2025Detalles


Solicitar un pedido a granel

Seleccione un Tamaño

Cambiar Vistas
250 MG
$51.20
1 G
$182.00
5 G
$567.00

About This Item

Fórmula empírica (notación de Hill):
C34H32N4Na2O4
Número de CAS:
Peso molecular:
606.62
Beilstein:
5227034
Número CE:
Número MDL:
Código UNSPSC:
12352103
ID de la sustancia en PubChem:
NACRES:
NA.23

$51.20


Disponible para envío el14 de abril de 2025Detalles


Solicitar un pedido a granel

Ensayo

≥90% (HPLC)

Formulario

powder

λmáx.

406 nm

temp. de almacenamiento

2-8°C

cadena SMILES

[Na+].[Na+].Cc1c(CCC([O-])=O)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(C=C)c5C)c(C=C)c4C)c(C)c3CCC([O-])=O

InChI

1S/C34H34N4O4.2Na/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16,36-37H,1-2,9-12H2,3-6H3,(H,39,40)(H,41,42);;/q;2*+1/p-2/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;

Clave InChI

JZRNDUPVNXWZDY-HXFTUNQESA-L

¿Está buscando productos similares? Visita Guía de comparación de productos

Aplicación

Protoporphyrin disodium salt (PpIX) was used as a dye content for fluorescence spectroscopic characterization in a study. [1] The cytotoxic effect of PpIX on sarcoma 180 solid tumors cells was reported in a study. [2][3]

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Los clientes también vieron

Slide 1 of 3

1 of 3

Fluorescence spectroscopic characterization of salivary metabolites of oral cancer patients.
Yuvaraj M, et al.
Journal of Photochemistry and Photobiology. B, Biology, 130, 153-160 (2014)
Sonodynamic effects of protoporphyrin IX disodium salt on isolated sarcoma 180 cells
Liu Q, et al.
Ultrasonics, 45(1-4), 56-60 (2006)
Kiwamu Takahashi et al.
Anticancer research, 33(7), 2861-2866 (2013-06-20)
5-Aminolevulinic acid (ALA) is a precursor of heme. ALA is used as a photosensitive substance in photodynamic diagnosis (PDD) and photodynamic therapy (PDT) because heme metabolism is abnormal in tumor cells and a photosensitive metabolite of heme synthesis from ALA
Pan Wang et al.
Ultrasonics, 53(5), 935-942 (2013-02-19)
Protoporphyrin IX (PpIX) has been used as a sensitizer in photodynamic therapy (PDT) as well as in sonodynamic therapy (SDT). The photo-bleaching of PpIX has been well investigated in many experimental systems and some photo-products have also been identified in
Kana Unuma et al.
PloS one, 8(2), e56526-e56526 (2013-03-05)
Lipopolysaccharide (LPS)-induced myocardial dysfunction is caused, at least in part, by mitochondrial dysfunction. Mitochondrial dysfunction and the oxidative damage associated with it are scavenged through various cellular defense systems such as autophagy to prevent harmful effects. Our recent study has

Artículos

Novel Graphene‑Based Nanostructures Production, Functionalization, and Engineering

Questions

1–2 of 2 Questions  
  1. To study interaction of porphyrin with a protein, how should a solution of this compound be made for flourescence quenching?

    1 answer
    1. This is not an application that is tested internally, but there is evidence in literature (Iwunze MO. The fluorescence study of the quenching of nanoemulsion by protoporphyrin IX (PPIX). Material Sci & Eng. 2022;6(3):97‒99. DOI: 10.15406/mseij.2022.06.00185) that concentrations between 6.45 x 10-7 M to 3.24 x 10-6 M PPIX are effective for quenching. Another author describes the quenching of protein fluorescence by PPIX by using a solution concentration range of 1×10−5 M to 3×10−4 M excited at 280 nm and 1x10−5 M to 3×10−4 M excited at 295 nm (Characteristics of the Protoporphyrin IX Binding Sites on Human Serum Albumin Using Molecular Docking, Molecules 2016, 21(11), 1519).

      Helpful?

  2. What is the water solubility of PPIX-disodium?

    1 answer
    1. This chemical is known to be soluble in chloroform or methanol and slightly soluble in water. The concentration at which this product is solubilized is not determined.

      Helpful?

Reviews

No rating value

Active Filters

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico