125180

1-(3-Chlorophenyl)piperazine hydrochloride

99%

• Sinónimos: m-CPP
• Fórmula empírica (notación de Hill): C₁₀H₁₃ClN₂ · xHCl
• Número de CAS: 65369-76-8
• Peso molecular: 196.68 (free base basis)
• EC Number: 265-718-0
• MDL number: MFCD00039032
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847652
• NACRES: NA.22

Propiedades

• assay: 99%
• form: powder
• mp: 210-214 °C (dec.) (lit.)
• solubility: methanol: soluble
• SMILES string: Cl.Clc1cccc(c1)N2CCNCC2
• InChI: 1S/C10H13ClN2.ClH/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13;/h1-3,8,12H,4-7H2;1H
• InChI key: MHXPYWFZULXYHT-UHFFFAOYSA-N
• Gene Information: rat ... Htr1a(24473)

Descripción

General description

1-(3-Chlorophenyl)piperazine hydrochloride is sold as Ecstasy mimic tablets and is the major metabolite of the antidepressant medications trazodone and nefazodone.

Application

1-(3-Chlorophenyl)piperazine hydrochloride (CPP) has been used in determination of designer piperazines in urine specimens using GC-MS and LC-ESI-MS. CPP has been used to investigate the in vitro efficacy of newly synthesized compounds such as fluoroquinolones (norfloxacine and lomefloxacine) against Philasterides dicentrarchi .

Biochem/physiol Actions

1-(3-Chlorophenyl)piperazine induces hypophagia in food-deprived and freely feeding rats. CPP has affinity for 11 neurotransmitter receptor binding sites in human brain membranes.

5-HT_2c serotonin receptor agonist; metabolite of trazodone.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves