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MilliporeSigma

THRB

thyroid hormone receptor, beta

Sinónimos:
C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2
Especie:
Human THRB (7068), Mouse Thrb (21834), Rat Thrb (24831), Domestic Rabbit THRB (100303763), chicken THRB (396431), cow THRB (788329), domestic cat THRB (101084821), Horse THRB (100051615), dog THRB (403599), naked mole-rat Thrb (101719651) ...Más
ID UniProtKB:
P10828, B3KU79, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
ID del gen:
  • Human(7068) Summary: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(21834) thyroid hormone receptor beta
  • Rat(24831) thyroid hormone receptor beta
  • Domestic Rabbit(100303763) thyroid hormone receptor, beta
  • chicken(396431) thyroid hormone receptor, beta
  • cow(788329) thyroid hormone receptor, beta
  • domestic cat(101084821) thyroid hormone receptor, beta
  • Horse(100051615) thyroid hormone receptor, beta
  • dog(403599) thyroid hormone receptor, beta
  • naked mole-rat(101719651) thyroid hormone receptor, beta
  • domestic guinea pig(100721125) thyroid hormone receptor, beta
  • Zebrafish(30607) thyroid hormone receptor beta

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
T-074
3,3′,5-Triyodo-L-tironina, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
T-073
L-Tiroxina, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
1365000
Levotiroxina, United States Pharmacopeia (USP) Reference Standard,
Especie
human
1365065
Levothyroxine sodium hydrate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
1368008
Liotironina, United States Pharmacopeia (USP) Reference Standard,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
T6397
3,3′,5-Triiodo-L-thyronine sodium salt, powder, BioReagent, suitable for cell culture,
Especie
rat, human
T2877
3,3′,5-Triyodo-L-tironina, ≥95% (HPLC), powder,
Especie
rat, human
T5516
3,3′,5-Triiodo-L-thyronine sodium salt, γ-irradiated, powder, suitable for, suitable for cell culture,
Especie
rat, human
T7650
3,3′,5-Triiodothyroacetic acid, ≥90%,
Especie
rat, human
T2376
L-Tiroxina, ≥98% (HPLC),
Especie
human, mouse, rat

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
ABN25
Anti-Thyroid Hormone Receptor β-1 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
SAB4502969
Anti-Thyroid Hormone Receptor β, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot
HPA061035
Anti-THRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
SAB2501038
Anti-THRB antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
canine, human, mouse, rat
Aplicación
ELISA
western blot
SAB4504736
Anti-phospho-TR-β1 (pSer142) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
T6397
3,3′,5-Triiodo-L-thyronine sodium salt, powder, BioReagent, suitable for cell culture,
Especie
rat, human
T2877
3,3′,5-Triyodo-L-tironina, ≥95% (HPLC), powder,
Especie
rat, human
T5516
3,3′,5-Triiodo-L-thyronine sodium salt, γ-irradiated, powder, suitable for, suitable for cell culture,
Especie
rat, human

esiRNA

Referencia del producto
Descripción
Especie
EHU083461
MISSION® esiRNA, targeting human THRB,
Especie
human