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PARP1

poly (ADP-ribose) polymerase 1

Sinónimos:
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1
Especie:
ID UniProtKB:
ID del gen:
  • Human(142) Summary: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11545) poly (ADP-ribose) polymerase family, member 1
  • Rat(25591) poly (ADP-ribose) polymerase 1
  • Thale Cress(817690) poly [ADP-ribose] polymerase 2
  • chicken(396199) poly (ADP-ribose) polymerase 1
  • Zebrafish(560788) poly (ADP-ribose) polymerase family, member 1
  • sheep(100135697) poly (ADP-ribose) polymerase 1
  • domestic cat(101081434) poly (ADP-ribose) polymerase 1
  • Horse(100058523) poly (ADP-ribose) polymerase 1
  • dog(490385) poly (ADP-ribose) polymerase 1
  • domestic guinea pig(100733925) poly (ADP-ribose) polymerase 1
  • naked mole-rat(101703207) poly (ADP-ribose) polymerase 1
  • cow(286764) poly (ADP-ribose) polymerase 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PARP (Cleaved-Asp214) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
ELISA
western blot
Anti-Poly ADP-ribose Antibody, clone 10H, clone 10H, from mouse,
Reactividad de especies
human
Aplicación
immunofluorescence
immunoprecipitation (IP)

western blot
Monoclonal Anti-PARP1 antibody produced in mouse, clone 3G4, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

western blot
Anti-PARP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-cleaved PARP-1 Antibody, clone 2G13 Antibody, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey
Aplicación
flow cytometry
immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Benzamide, 99%,
Especie
human
3-Aminobenzamide, ≥99% (TLC),
Especie
mouse
Benzamide, purified by sublimation, ≥99.5%,
Especie
human
6-(5H)-Phenanthridinone, technical grade,
Especie
human
Nicotinamide, BioReagent, suitable for cell culture, suitable for insect cell culture,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
PARP-1 human, recombinant, expressed in E. coli,
Especie
human
PARP1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Especie
human
Monoclonal Anti-PARP1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2220, purified immunoglobulin, buffered aqueous glycerol solution,
Especie
human
Monoclonal Anti-PARP1, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2209, purified immunoglobulin, buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PARP1,
Especie
human
MISSION® esiRNA, targeting mouse Parp1,
Especie
mouse