Saltar al contenido
MilliporeSigma

IDH2

isocitrate dehydrogenase 2 (NADP+), mitochondrial

Sinónimos:
D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH
Especie:
ID UniProtKB:
ID del gen:
  • Human(3418) Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeq, Jul 2008]
  • Mouse(269951) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Rat(361596) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Thale Cress(816218) Isocitrate dehydrogenase [NAD] regulatory subunit 2
  • Zebrafish(386951) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • dog(479043) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • chicken(431056) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Domestic Rabbit(100340796) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • sheep(101102843) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • cow(327669) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • domestic cat(101082315) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • naked mole-rat(101708667) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • domestic guinea pig(100726681) isocitrate dehydrogenase 2 (NADP+), mitochondrial

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-IDH2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
bovine, canine, human, mouse, rat
Aplicación
ELISA
immunohistochemistry

western blot
Monoclonal Anti-IDH2 antibody produced in mouse, clone 5F11, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry

western blot
Anti-IDH2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot
Anti-IDH2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-IDH2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Kits

Referencia del producto
Descripción
Especie
IDH Activity Assay Kit, sufficient for 100 colorimetric tests,
Especie
mouse, rat, human

Proteins

Referencia del producto
Descripción
Especie
IDH2, FLAG® -Tag, recombinant, expressed in baculovirus infected Sf9 cells,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human IDH2,
Especie
human
MISSION® esiRNA, targeting mouse Idh2,
Especie
mouse