ESR2
estrogen receptor 2 (ER beta)
Sinónimos:
ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
Especie:
Human ESR2 (2100), Mouse Esr2 (13983), Rat Esr2 (25149), dog ESR2 (403639), chicken ESR2 (395575), domestic guinea pig Esr2 (100731304), Domestic Rabbit ESR2 (100346748), domestic cat ESR2 (101086317), Horse ESR2 (100033964), cow ESR2 (281146) ...Más
ID UniProtKB:
ID del gen:
- Human(2100) Summary: This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]
- Mouse(13983) estrogen receptor 2 (beta)
- Rat(25149) estrogen receptor 2 (ER beta)
- dog(403639) estrogen receptor 2 (ER beta)
- chicken(395575) estrogen receptor 2 (ER beta)
- domestic guinea pig(100731304) estrogen receptor 2 (ER beta)
- Domestic Rabbit(100346748) estrogen receptor 2 (ER beta)
- domestic cat(101086317) estrogen receptor 2 (ER beta)
- Horse(100033964) estrogen receptor 2 (ER beta)
- cow(281146) estrogen receptor 2 (ER beta)
- Goat(100860823) estrogen receptor 2 (ER beta)
- sheep(443066) estrogen receptor 2 (ER beta)
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Small Molecule - Activator
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Descripción
Especie
βDinucleótido de β-nicotinamida y adenina hydrate, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast,
Especie
human
Small Molecule - Agonist
Small Molecule - Allosteric Modulator
Referencia del producto
Descripción
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Raloxifene Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Small Molecule - Antagonist
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Estrogen Receptor β Antibody, clone 68-4, rabbit monoclonal, clone 68-4, Upstate®, from rabbit,
Reactividad de especies
human
Aplicación
immunoprecipitation (IP)
western blot
western blot
Monoclonal Anti-ESR2 antibody produced in mouse, ,
Reactividad de especies
human, monkey, mouse
Aplicación
ChIP
dot blot
flow cytometry
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
dot blot
flow cytometry
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-Estrogen Receptor-β antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-Estrogen Receptor β Antibody, clone 9.88, clone 9.88, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunoprecipitation (IP)
western blot
western blot
Anti-ESR2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
western blot
Cell Lines
Referencia del producto
Descripción
Especie
Small Molecule - Mixed Agonist/Antagonist
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Especie
esiRNA
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Descripción
Especie