ESR1

estrogen receptor 1

Sinónimos:

ER, ESR, ESRA, ESTRR, Era, NR3A1

Especie:

Human ESR1 (2099), Mouse Esr1 (13982), Rat Esr1 (24890), domestic cat ESR1 (552888), dog ESR1 (403640), chicken ESR1 (396099), Thale Cress ESR1 (837856), Horse ESR1 (791249), Zebrafish esr1 (259252), cow ESR1 (407238) ...Más

ID UniProtKB:

P03372, Q13511, Q14276, Q5T5H7, Q6MZQ9, Q9NU51, Q9UDZ7, Q9UIS7

ID del gen:

Human(2099) Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
Mouse(13982) estrogen receptor 1 (alpha)
Rat(24890) estrogen receptor 1
domestic cat(552888) estrogen receptor 1
dog(403640) estrogen receptor 1
chicken(396099) estrogen receptor 1
Thale Cress(837856) ethylene-responsive transcription factor ESR1
Horse(791249) estrogen receptor 1
Zebrafish(259252) estrogen receptor 1
cow(407238) estrogen receptor 1
Goat(100860768) estrogen receptor 1
sheep(443228) estrogen receptor 1
domestic guinea pig(100713276) estrogen receptor 1

Productos (202)
Artículos con revisión científica externa. (1,024)

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Small Molecule - Activator

Referencia del producto

Descripción

Especie

131083

4-Phenylazophenol, 98%,

Especie

human

N0632

βDinucleótido de β-nicotinamida y adenina sodium salt, ,

Especie

human

139939

trans-Stilbene, 96%,

Especie

human, rat

43410

βDinucleótido de β-nicotinamida y adenina hydrate, ≥95% (HPLC),

Especie

human

N7004

βDinucleótido de β-nicotinamida y adenina hydrate, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast,

Especie

human

Small Molecule - Agonist

Referencia del producto

Descripción

Especie

E-060

17β-Estradiol solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®,

Especie

human

1250008

β-Estradiol, United States Pharmacopeia (USP) Reference Standard,

Especie

human

E-075

Estrone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®,

Especie

human

1260001

Etinil estradiol, United States Pharmacopeia (USP) Reference Standard,

Especie

human

PHR1353

β-Estradiol, Pharmaceutical Secondary Standard; Certified Reference Material,

Especie

human

Small Molecule - Allosteric Modulator

Referencia del producto

Descripción

Especie

1643306

Tamoxifen citrate, United States Pharmacopeia (USP) Reference Standard,

Especie

human

85256

Tamoxifeno, analytical standard,

Especie

human

06734

Tamoxifeno, certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,

Especie

human

BP1225

Tamoxifen citrate, British Pharmacopoeia (BP) Reference Standard,

Especie

human

T0014000

Tamoxifen citrate, European Pharmacopoeia (EP) Reference Standard,

Especie

human

Small Molecule - Antagonist

Referencia del producto

Descripción

Especie

524980

Dibutyl phthalate, 99%,

Especie

mouse

308501

Benzyl butyl phthalate, 98%,

Especie

mouse

Z2125

Zearalenone, fungal mycotoxin,

Especie

mouse

290823

4-tert-Octylphenol, 97%,

Especie

mouse

49085

Atrazine, analytical standard,

Especie

mouse

Antibodies

Referencia del producto

Descripción

Reactividad de especies

Aplicación

HPA000449

Anti-ESR1 antibody produced in rabbit, Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,

Reactividad de especies

human

Aplicación

immunofluorescence
immunohistochemistry
western blot

SAB4500813

Anti-Estrogen Receptor-α antibody produced in rabbit, affinity isolated antibody,

Reactividad de especies

human

Aplicación

ELISA
immunohistochemistry
western blot

249R-1

Estrogen Receptor (SP1) Rabbit Monoclonal Antibody, ,

Reactividad de especies

Aplicación

04-1564

Anti-Estrogen Receptor α Antibody, clone F3-A, ascites fluid, clone F3-A, from mouse,

Reactividad de especies

human, mouse, rat

Aplicación

immunocytochemistry
western blot

AMAB90867

Monoclonal Anti-ESR1 antibody produced in mouse, Prestige Antibodies^® Powered by Atlas Antibodies, clone CL1196, purified immunoglobulin, buffered aqueous glycerol solution,

Reactividad de especies

human

Aplicación

immunofluorescence
immunohistochemistry
western blot