HPLC Analysis of 3,4-Methylenedioxypyrovalerone (MDPV) Enantiomers on Astec® CHIROBIOTIC® V2
Materials
analytical column
standard
MDPBP hydrochloride solution
1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®CONDITIONS
column
Astec CHIROBIOTIC V2 15 cm x 4.6 mm I.D., 5 μm particles (15023AST)
mobile phase
[A] methanol; [B] water; [C] acetic acid; [D] ammonium hydroxide; (95:5:0.1:0.02, A:B:C:D)
flow rate
1 mL/min
pressure
1100 psi (70 bar)
column temp.
20 °C
detector
UV, 235 nm
injection
5 μL
sample
100 μg/mL in methanol
Description
Analysis Note
3,4-Methylenedioxypyrovalerone, also known as MDPV, Mtv, or Super Coke, is a new designer drug and stimulant with cases of abuse reported in Europe and the US. In mid- to late-2010, MDPV started appearing in the US as a legal drug alternative marketed as “bath salts” under names including Ivory Wave, Tranquility, and Cloud 9. Astec CHIROBIOTIC V2, based on vancomycin CSP, provided resolution of the enatiomers. CRMs from Cerillliant provided reliable identification and quantification.
Legal Information
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CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC