HPLC Analysis of 3′,4′-Methylenedioxy-α-pyrrolidinopropiophenone (MDPPP) Enantiomers on Astec® CHIROBIOTIC® V2
Materials
analytical column
CONDITIONS
column
Astec CHIROBIOTIC V2 15 cm x 4.6 mm I.D., 5 μm particles (15023AST)
mobile phase
[A] methanol; [B] water; [C] acetic acid; [D] ammonium hydroxide; (95:5:0.1:0.02, A:B:C:D)
flow rate
1 mL/min
pressure
1100 psi (70 bar)
column temp.
20 °C
detector
UV, 251 nm
injection
5 μL
sample
100 μg/mL in methanol
Description
Analysis Note
3′,4′-Methylenedioxy-a-pyrrolidinopropiophenone, also known as MDPPP, is a synthetic cathinone found in numerous bath salt blends under the street name NRG-1. This designer drug first emerged in Germany in the late 1990s and early 2000s as an ingredient in imitation ecstasy pills. Astec CHIROBIOTIC V2, based on vancomycin CSP, provided resolution of the enatiomers. CRMs from Cerillliant provided reliable identification and quantification.
Legal Information
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CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC