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Ginsenoside Rb1 Inhibits Doxorubicin-Triggered H9C2 Cell Apoptosis

Biomolecules & therapeutics (2016-11-11)
Yaxin Zhang, Yuguang Wang, Zengchun Ma, Qiande Liang, Xianglin Tang, Hongling Tan, Chengrong Xiao, Yue Gao
ABSTRACT

Doxorubicin (DOX) is a highly effective chemotherapeutic agent; however, the dose-dependent cardiotoxicity associated with DOX significantly limits its clinical application. In the present study, we investigated whether Rb1 could prevent DOX-induced apoptosis in H9C2 cells

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MISSION® esiRNA, targeting human AHR, RP11-507K12.1