- Development of a catalytic aromatic decarboxylation reaction.
Development of a catalytic aromatic decarboxylation reaction.
Organic letters (2007-06-05)
Joshua S Dickstein, Carol A Mulrooney, Erin M O'Brien, Barbara J Morgan, Marisa C Kozlowski
PMID17542594
ABSTRACT
A palladium-catalyzed aromatic decarboxylation reaction has been developed. With electron-rich aromatic acids, the reaction proceeds efficiently under fairly mild conditions in good yields. The method was useful with complex functionalized substrates containing hindered carboxylic acids.
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