- Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR.
Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR.
Genomics (1992-12-01)
D J Vandenbergh, A M Persico, A L Hawkins, C A Griffin, X Li, E W Jabs, G R Uhl
PMID1478653
ABSTRACT
The human dopamine transporter (DAT1) gene is localized to chromosome 5p15.3 by in situ hybridization and PCR amplification of rodent somatic cell hybrid DNA. Analysis of a 40-bp repeat in the 3' untranslated region of the message revealed variable numbers of the repeat ranging from 3 to 11 copies. These results will aid in the investigation of a role for this gene in genetic disorders of the dopaminergic system in humans.