Skip to Content
MilliporeSigma
  • Studies on the anti-phospholipase A2 and anti-inflammatory activities of a synthetic nonapeptide from uteroglobin.

Studies on the anti-phospholipase A2 and anti-inflammatory activities of a synthetic nonapeptide from uteroglobin.

Arzneimittel-Forschung (1991-03-01)
M Marastoni, S Salvadori, G Balboni, V Scaranari, V Santagada, P Romualdi, S Ferri, R Tomatis
PMID1867659
ABSTRACT

The nonapeptide H-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH (antiflammin), corresponding to a high amino acid similarity region of uteroglobin was prepared by solution and solid phase synthesis. The peptide do not inhibit pancreatic phospholipase A2 in vitro and the carrageenin-induced oedema in vivo.