Skip to Content
MilliporeSigma
  • Laparoscopic lymphatic roadmapping with blue dye and radioisotope in colon cancer.

Laparoscopic lymphatic roadmapping with blue dye and radioisotope in colon cancer.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2011-12-07)
P P Bianchi, W Petz, L Casali
ABSTRACT

Lymphatic mapping (LM) and sentinel lymph node (SLN) identification by blue dye in colon cancer is a procedure feasible during minimally invasive surgery, with good specificity, but still a low sensitivity (78% in our series). These results are in accordance with the literature and have limited more widespread diffusion of the method, both as a tool for upstaging and more controversially, as a potential roadmap to a tailored lymphadenectomy. It is possible to improve the results of LM with careful selection of patients and by the use of an intraoperative gamma camera. The preliminary results of intra-operative lymphoscintigraphy are promising in a well-selected small group of patients, with high levels of sensitivity and specificity. If these results are confirmed in further prospective analyses, it may be possible to undertake selected, tailored lymphadenectomy.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Patent blue VF sodium salt, for microscopy
Sigma-Aldrich
Patent Blue VF, Dye content 50 %