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  • Stereoselective functionalization of the 1'-position of 4'-thionucleosides.

Stereoselective functionalization of the 1'-position of 4'-thionucleosides.

Organic letters (2006-09-08)
Prashantha Gunaga, Hea Ok Kim, Hyuk Woo Lee, Dilip K Tosh, Jae-Sang Ryu, Sun Choi, Lak Shin Jeong
ABSTRACT

Stereoselective synthesis of novel 1'-alpha-substituted-4'-thionucleosides was achieved starting from D-gulonic acid gamma-lactone via stereoselective nucleophilic substitution.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
L-Gulonic acid γ-lactone, 95%