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  • [Genotoxic and radioprotective properties of 2,5-diphenyloxazole and its derivatives on mice DNA structure in vivo].

[Genotoxic and radioprotective properties of 2,5-diphenyloxazole and its derivatives on mice DNA structure in vivo].

Radiatsionnaia biologiia, radioecologiia (2005-04-07)
G P Zhizhina, T M Zavarykina, E B Burlakova, V G Noskov, F S Dukhovich
ABSTRACT

The effects of 2,5-diphenyloxazole ad its derivatives suggested as nontraditional radioprotectors on mice spleen DNA structure were studied. The effects of these compounds were studied on intraperitoneal injection with and without subsequent X-ray exposure of mice to a dose of 12 cGy. The formation of double-strand breaks and DNA conformation change (by adsorption on NC filters) were recorded. A genotoxic effect of 2,5-diphenyloxazole and its derivatives, a nonlinearity of their dose-response relationships and different effects depending on the substance concentration were found. Some of the compounds exhibited radioprotective properties in certain concentration.

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Product Description

Sigma-Aldrich
2,5-Diphenyloxazole, suitable for liquid scintillation spectrometry
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20 mL
100 mL
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Sigma-Aldrich
2,5-Diphenyloxazole, 99%, suitable for scintillation
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
20 mL
100 mL
In Stock
Details...
$51.90
6 x 20 mL
Estimated to ship on March 21, 2025
$60.60