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  • Trifluoromethanesulfonic anhydride-promoted alpha-bromination of ketones with grignard reagent or magnesium bromide.

Trifluoromethanesulfonic anhydride-promoted alpha-bromination of ketones with grignard reagent or magnesium bromide.

Chemical & pharmaceutical bulletin (2001-01-06)
T Nishiyama, Y Ono, S Kurokawa, S Kimura
PMID11145159
ABSTRACT

The direct alpha-bromination of various ketones using trifluoromethanesulfonic anhydride and Grignard reagent or magnesium bromide in ether gave the corresponding alpha-bromo ketones in moderate to good yields under mild reaction conditions.

MATERIALS
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Product Description
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