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1345159

USP

Ioxaglic acid

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

N-(2-Hydroxyethyl)-2,4,6-triiodo-5-{2-[2,4,6-triiodo-3-(N-methylacetamido)-5-(methylcarbamoyl)benzamido]acetamido}isophthalamic acid

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About This Item

Empirical Formula (Hill Notation):
C24H21I6N5O8
CAS Number:
59017-64-0
Molecular Weight:
1268.88
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

ioxaglic acid

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/C24H21I6N5O8/c1-7(37)35(3)20-17(29)10(21(39)31-2)13(25)11(18(20)30)23(41)33-6-8(38)34-19-15(27)9(22(40)32-4-5-36)14(26)12(16(19)28)24(42)43/h36H,4-6H2,1-3H3,(H,31,39)(H,32,40)(H,33,41)(H,34,38)(H,42,43)

InChI key

TYYBFXNZMFNZJT-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ioxaglic acid USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Ioxaglate Meglumine and Ioxaglate Sodium Injection

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M J Turunen et al.
Journal of biomechanics, 45(3), 497-503 (2011-12-31)
In clinical arthrographic examination, strong hypertonic contrast agents are injected directly into the joint space. This may reduce the stiffness of articular cartilage, which is further hypothesized to lead to overload-induced cell death. We investigated the cell death in articular
Topical intranasal ioxaglate meglumine 39.3% and ioxaglate sodium 19.6% (Hexabrix) reduces the acute response to nasal challenge with allergen.
Shilpa Vishwanath et al.
The Journal of allergy and clinical immunology, 128(1), 219-221 (2011-03-19)
Hye Jin Yoo et al.
Radiology, 261(3), 805-812 (2011-09-24)
To investigate the diagnostic potential of delayed contrast material-enhanced computed tomography (CT) of articular cartilage in quantification of glycosaminoglycan (GAG) concentration in normal and degenerated articular cartilage ex vivo by using a clinical CT scanner. This study was exempted by
K E M Benders et al.
Osteoarthritis and cartilage, 18(12), 1586-1591 (2010-10-19)
Equilibrium Partitioning of an Ionic Contrast agent with microcomputed tomography (EPIC-μCT) is a non-invasive technique to quantify and visualize the three-dimensional distribution of glycosaminoglycans (GAGs) in fresh cartilage tissue. However, it is unclear whether this technique is applicable to already
P N Bansal et al.
Osteoarthritis and cartilage, 19(8), 970-976 (2011-05-10)
The purpose of this study is to evaluate the effect of contrast agent charge on the contrast agent uptake ratio (CUR) in cartilage and to image the naturally occurring variations in glycosaminoglycan (GAG) content present in bovine articular cartilage. In
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