1269458

Fenoldopam mesylate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Fenoldopam methanesulfonate
• Empirical Formula (Hill Notation): C₁₆H₁₆ClNO₃ · CH₄O₃S
• CAS Number: 67227-57-0
• Molecular Weight: 401.86
• MDL number: MFCD04112986
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749837
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: fenoldopam
• manufacturer/tradename: USP
• mp: 271 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: CS(O)(=O)=O.Oc1ccc(cc1)C2CNCCc3c(Cl)c(O)c(O)cc23
• InChI: 1S/C16H16ClNO3.CH4O3S/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21;1-5(2,3)4/h1-4,7,13,18-21H,5-6,8H2;1H3,(H,2,3,4)
• InChI key: CVKUMNRCIJMVAR-UHFFFAOYSA-N
• Gene Information: human ... DRD1(1812)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Fenoldopam mesylate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Fenoldopam Mesylate Injection

Biochem/physiol Actions

Fenoldopam mesylate is a selective dopamine D₁ receptor agonist used as an antihypertensive agent. It is an agonist for D₁-like dopamine receptors and binds with moderate affinity to α2-adrenoceptors. It has no significant affinity for D₂-like receptors, α1 and α-adrenoceptors, 5HT₁ and 5HT₂ receptors, or muscarinic receptors. Fenoldopam mesylate causes peripheral vasodilation by stimulating dopamine-1receptors and α2-adrenoceptors, increasing renal blood flow.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H317,H319
• pcodes: P280 - P301 + P312 + P330 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable