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RAB0600

Sigma-Aldrich

Human A2M / Alpha-2-macroglobulin ELISA Kit

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 ng/mL
standard curve range: 12.29-3000 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... A2M(2)

Related Categories

General description

Human α-2-macroglobulin (α2M/A2M), a large tetrameric glycoprotein, is abundantly seen in plasma. It possesses anti-proteinase activity. A2M acts as a vital indicator in detecting thrombotic diseases. It plays a major role in coagulation and fibrinolysis systems. α2M may have the potential to be a new biomarker and therapeutic target for steroid-induced femoral head necrosis (SINFH). The A2M ELISA kit can be used for the quantitative measurement of α-2-macroglobulin in cell culture supernatants, plasma, and serum.
The A2M ELISA kit provides for the quantitative measurement of Alpha-2-macroglobulin in Cell Culture Supernatants, Plasma and Serum.

Application

Human A2M/Alpha-2-macroglobulin ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) to confirm the presence of α-2-macroglobulin (A2M) in the analyzed saliva pools.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Shan-Hong Fang et al.
Orthopaedic surgery, 11(3), 481-486 (2019-06-28)
The present study aimed to identify the relationship of α-2-macroglobulin and microvascular vessel pathology with steroid-induced femoral head necrosis in the Southeast Chinese population. This study enrolled 40 patients diagnosed with steroid-induced necrosis of the femoral head. Patients had various
Romina Hernández-Olivos et al.
Scientific reports, 11(1), 15646-15646 (2021-08-04)
There are currently no preventative options for recurrent aphthous stomatitis, and the only available treatments are palliative. This is partly due to a poor understanding of its etiopathogenesis. In this case-control study, we characterized the salivary proteome of patients with
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PloS one, 14(1), e0210172-e0210172 (2019-01-18)
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