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E3625

Sigma-Aldrich

16-Epiestriol

≥93% (HPLC)

Synonym(s):

1,3,5(10)-Estratriene-3,16β,17β-triol, 16β-Hydroxy-17β-estradiol, 3,16β,17β-Trihydroxy-1,3,5(10)-estratriene

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100 MG
$359.00

$359.00

Available to ship onApril 10, 2025Details

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100 MG
$359.00

About This Item

Empirical Formula (Hill Notation):
C18H24O3
CAS Number:
547-81-9
Molecular Weight:
288.38
EC Number:
208-937-9
MDL number:
MFCD00067609
UNSPSC Code:
12352202
PubChem Substance ID:
24894522
NACRES:
NA.77

$359.00

Available to ship onApril 10, 2025Details

Request a Bulk Order

Quality Level

200

assay

≥93% (HPLC)

form

powder

solubility

ethanol: 0.98-1.02 mg/mL, clear, colorless to faintly yellow

shipped in

ambient

storage temp.

room temp

SMILES string

CC12CCC3C(CCc4cc(O)ccc34)C1CC(O)C2O

InChI

1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3

InChI key

PROQIPRRNZUXQM-UHFFFAOYSA-N

Biochem/physiol Actions

16-Epiestriol is found naturally in various animals, plants, and fungal yeast. It potentially inhibits the growth of colistins and carbapenem-resistant A. baumannii [1]
16-Epiestriol, an estradiol metabolite, possesses anti-inflammatory properties but no glycogenic properties.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000395817
0000321141
0000299636
0000395817
0000265846

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Sally B Coburn et al.
Cancer causes & control : CCC, 30(1), 75-86 (2018-12-07)
The comparability between serum, plasma, and urinary measurements of estrogen metabolites via liquid chromatography-tandem mass spectrometry (LC-MS/MS) has not been largely explored, and it is unclear if urinary LC-MS/MS measurements are suitable surrogates of circulating levels. Serum, plasma (EDTA and
Xiaoguang Sunny Li et al.
Talanta, 178, 464-472 (2017-11-16)
Accurate quantitation of estrogens (i.e, estrone (E1), estradiol (E2) and estriol (E3)) is valuable for clinical assessment of human health and disease. Alterations in estrogen levels have been implicated in numerous pathological conditions. However, inadequacies in sensitivity and specificity, cumbersome
Ju-Yeon Moon et al.
BMC clinical pathology, 13(1), 25-25 (2013-10-26)
Estrogen metabolism may be associated with the pathophysiological development of papillary thyroid carcinoma (PTC). To evaluate the differential estrogen metabolism between benign and malignant PTCs, estrogen profiling by gas chromatography-mass spectrometry was applied to urine samples from postmenopausal patients with
Xia Xu et al.
Genome medicine, 4(4), 31-31 (2012-05-02)
Endogenous estrogens and estrogen metabolites play an important role in the pathogenesis and development of human breast, endometrial, and ovarian cancers. Increasing evidence also supports their involvement in the development of certain lung, colon and prostate cancers. In this study
Sinosh Skariyachan et al.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 82, 104314-104314 (2020-04-09)
The current study aimed to identify putative drug targets of multidrug resistant Acinetobacter baumannii (MDRAb) and study the therapeutic potential of natural epiestriol-16 by computer aided virtual screening and in vitro studies. The clinical isolates (n = 5) showed extreme dug resistance
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