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D9753

Sigma-Aldrich

DL-3,4-Dihydroxyphenyl glycol

Synonym(s):

DL-α,β,3,4-Tetrahydroxyphenethyl alcohol, DL-β,3,4-Trihydroxyphenethyl alcohol

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About This Item

Empirical Formula (Hill Notation):
C8H10O4
CAS Number:
28822-73-3
Molecular Weight:
170.16
EC Number:
249-260-9
MDL number:
MFCD00004702
UNSPSC Code:
12352106
PubChem Substance ID:
24894324
NACRES:
NA.25

form

powder

storage temp.

−20°C

SMILES string

OCC(O)c1ccc(O)c(O)c1

InChI

1S/C8H10O4/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8-12H,4H2

InChI key

MTVWFVDWRVYDOR-UHFFFAOYSA-N

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Osnat Ben-Shahar et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(2), 495-506a-495-506a (2013-01-11)
Anomalies in prefrontal cortex (PFC) function are posited to underpin difficulties in learning to suppress drug-seeking behavior during abstinence. Because group 1 metabotropic glutamate receptors (mGluRs) regulate drug-related learning, we assayed the consequences of extended access to intravenous cocaine (6
Adrianne R Wilson-Poe et al.
Neuropharmacology, 66, 348-354 (2012-07-10)
Metabotropic glutamate (mGlu) receptors modulate pain from within the midbrain periaqueductal grey (PAG). In the present study, the postsynaptic mGlu receptor mediated effects on rat PAG neurons were examined using whole-cell patch-clamp recordings in brain slices. The selective group I
David S Goldstein et al.
Brain : a journal of neurology, 135(Pt 6), 1900-1913 (2012-03-28)
Central catecholamine deficiency characterizes α-synucleinopathies such as Parkinson's disease. We hypothesized that cerebrospinal fluid levels of neuronal metabolites of catecholamines provide neurochemical biomarkers of these disorders. To test this hypothesis we measured cerebrospinal fluid levels of catechols including dopamine, norepinephrine
G Eisenhofer et al.
The Journal of clinical endocrinology and metabolism, 68(2), 247-255 (1989-02-01)
Dihydroxyphenylalanine (DOPA) is the immediate product of the rate-limiting step in catecholamine biosynthesis, hydroxylation of tyrosine. This study examined whether plasma concentrations of DOPA are related to tyrosine hydroxylase activity. Plasma concentrations of DOPA, norepinephrine, and the norepinephrine metabolites 3,4-dihydroxyphenylglycol
Andrii Rudenko et al.
Neuron, 79(6), 1109-1122 (2013-09-21)
The ten-eleven translocation (Tet) family of methylcytosine dioxygenases catalyze oxidation of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) and promote DNA demethylation. Despite the abundance of 5hmC and Tet proteins in the brain, little is known about the functions of the neuronal
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