All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C15H12I2O4
CAS Number:
Molecular Weight:
510.06
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
storage temp.
2-8°C
SMILES string
OC(=O)CCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
Looking for similar products? Visit Product Comparison Guide
Biochem/physiol Actions
DITPA, an analog of L-thyroxine, has inotropic but not chronotropic effects on heart muscle. It also stimulates myocardial angiogenesis after infarction by interaction with integrin αvཪ3 at the cell surface.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Najah R Hadi et al.
BMC nephrology, 12, 70-70 (2011-12-27)
Acute renal failure (ARF) is an important clinical problem with a high mortality and morbidity. One of the primary causes of ARF is ischemia/reperfusion (I/R). Inflammatory process and oxidative stress are thought to be the major mechanisms causing I/R. MK-886
Peter H Spooner et al.
Journal of cardiovascular pharmacology, 44(4), 453-459 (2004-09-30)
This study was designed to determine if the thyroid hormone analog 3,5 diiodothyropropionic acid (DITPA), now in clinical trials for heart failure, alters endothelial function after myocardial infarction (MI). Three weeks after MI, adult Sprague-Dawley rats were randomly assigned to
Abdelrahman A Abohashem-Aly et al.
The Journal of surgical research, 171(2), 379-385 (2011-06-11)
Thyroid hormone can have positive effects on the cardiovascular system but its therapeutic potential is limited secondary to its adverse effects. DITPA (3,5-diiodothyroproprionic acid) is a synthetic thyroid hormone analog with positive inotropic effects similar to thyroid hormone but with
Reza Arsanjani et al.
Journal of molecular and cellular cardiology, 51(4), 506-511 (2011-01-11)
Thyroid hormone has unique properties affecting the heart, and the vasculature and cholesterol metabolism. There is interest in using thyromimetic agents as possible treatment options for heart failure based on data demonstrating the ability of these agents to improve systolic
M A Hassan Talukder et al.
American journal of physiology. Heart and circulatory physiology, 300(2), H702-H711 (2010-12-07)
There is emerging evidence that treatment with thyroid hormone (TH) can improve postischemic cardiac function. 3,5-Diiodothyropropionic acid (DITPA), a TH analog, has been proposed to be a safer therapeutic agent than TH because of its negligible effects on cardiac metabolism
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
