Skip to Content
MilliporeSigma
All Photos(1)

Documents

A002

Sigma-Aldrich

N6-Cyclohexyladenosine

Synonym(s):

CHA

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C16H23N5O4
CAS Number:
36396-99-3
Molecular Weight:
349.38
MDL number:
MFCD00036808
UNSPSC Code:
12352204
PubChem Substance ID:
329770564

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NC4CCCCC4)ncnc23

InChI

1S/C16H23N5O4/c22-6-10-12(23)13(24)16(25-10)21-8-19-11-14(17-7-18-15(11)21)20-9-4-2-1-3-5-9/h7-10,12-13,16,22-24H,1-6H2,(H,17,18,20)/t10-,12-,13-,16-/m1/s1

InChI key

SZBULDQSDUXAPJ-XNIJJKJLSA-N

Looking for similar products? Visit Product Comparison Guide

General description

N6-Cyclohexyladenosine belongs to the class of new generation thermolytic agents.

Biochem/physiol Actions

N6-Cyclohexyladenosine is an adenosine A1 receptor agonist. It prevents thermogenesis and other response such as shivering in response to cold. N6-Cyclohexyladenosine initiates hibernation in animals.

replaced by

Product No.
Description
Pricing

C9901

N6-Cyclohexyladenosine

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Modulation of conventional outflow facility by the adenosine A1 agonist N6-cyclohexyladenosine
Crosson CE, et al.
Investigative Ophthalmology & Visual Science, 46(10), 3795-3799 (2005)
Precise Control of Target Temperature Using N6-Cyclohexyladenosine and Real-Time Control of Surface Temperature
Laughlin BW, et al.
Therapeutic hypothermia and temperature management, 8(2), 108-116 (2018)
José Luis Albasanz et al.
The European journal of neuroscience, 26(12), 3501-3508 (2007-12-07)
The adenosine A(1) receptor (A(1)R)-adenylyl cyclase (AC) pathway was studied in post-mortem human frontal and occipital cortex from Pick's disease (PiD) cases and age-matched nondemented controls. In frontal cortex, the main brain area affected in PiD, A(1)Rs, determined by radioligand
Enbo Zhan et al.
American journal of physiology. Heart and circulatory physiology, 301(3), H1183-H1189 (2011-07-12)
All four adenosine receptor subtypes have been shown to play a role in cardioprotection, and there is evidence that all four subtypes may be expressed in cardiomyocytes. There is also increasing evidence that optimal adenosine cardioprotection requires the activation of
Matthew Edward Pamenter et al.
Brain research, 1213, 27-34 (2008-05-06)
Adenosine is a defensive metabolite that is critical to anoxic neuronal survival in the freshwater turtle. Channel arrest of the N-methyl-d-aspartate receptor (NMDAR) is a hallmark of the turtle's remarkable anoxia tolerance and adenosine A1 receptor (A1R)-mediated depression of normoxic
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service