SRP0414
PKLR Var2 active human
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym(s):
PK1, PKL, RPK, pyruvate kinase, liver and RBC
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About This Item
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biological source
human
recombinant
expressed in E. coli
assay
≥90% (SDS-PAGE)
form
aqueous solution
mol wt
59 kDa
packaging
pkg of 20 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... PKLR(5313)
General description
PKR (GenBank Accession No. NM_181871) full length, amino acids 2-543 (end) with N-terminal His-tag, MW=59 kDa, expressed in an E. coli expression system.
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Steven T Russell et al.
Experimental cell research, 315(1), 16-25 (2008-11-01)
Treatment of murine myotubes with high glucose concentrations (10 and 25 mM) stimulated protein degradation through the ubiquitin-proteasome pathway, and also caused activation (autophosphorylation) of PKR (double-stranded-RNA-dependent protein kinase) and eIF2alpha (eukaryotic initiation factor 2alpha). Phosphorylation of PKR and eIF2alpha
María J Bullido et al.
Neurobiology of aging, 29(8), 1160-1166 (2007-04-11)
Sporadic Alzheimer's disease (AD) appears to be the consequence of the interaction between combinations of genes and environmental factors (for example virus infections). To test this hypothesis, we are examining human genes relevant to herpes simplex virus type 1 (HSV-1)
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