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Key Documents

ML0010

Sigma-Aldrich

TCA Cycle Metabolite Library

Synonym(s):

Kreb′s Cycle Metabolite Library

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1 KIT
$833.00

$833.00

Estimated to ship onMay 17, 2025

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1 KIT
$833.00

About This Item

UNSPSC Code:
41116107
NACRES:
NA.25

$833.00

Estimated to ship onMay 17, 2025

Request a Bulk Order

storage temp.

−20°C

Quality Level

200

Application


  • Reinforcing the Evidence of Mitochondrial Dysfunction in Long COVID Patients Using a Multiplatform Mass Spectrometry-Based Metabolomics Approach.: This study utilizes an advanced metabolomics approach to understand mitochondrial dysfunction in long COVID patients, highlighting the application of the TCA Cycle Metabolite Library for in-depth biological analysis (Martinez et al., 2024).

  • OGDH and Bcl-xL loss causes synthetic lethality in glioblastoma.: This research explores the critical interactions in metabolic pathways, particularly the TCA cycle, affecting glioblastoma′s cellular metabolism and identifying potential therapeutic targets (Nguyen et al., 2024).

  • The interactions and biological pathways among metabolomics products of patients with coronary heart disease.: Demonstrates how metabolomics, including TCA cycle metabolites, can reveal complex biochemical pathways in coronary heart disease, offering insights into potential interventions (Chu et al., 2024).

  • Reduction in creatine metabolites in macrophages exposed to small molecule analogues of the anti-inflammatory parasitic worm product ES-62.: Investigates the impact of altered TCA cycle metabolites on macrophage biochemistry, providing a foundation for therapeutic research (Alanazi et al., 2024).

  • In-vivo tracking of deuterium metabolism in mouse organs using LC-MS/MS.: This study applies cutting-edge analytical techniques to trace metabolic pathways in vivo, including key TCA cycle intermediates, which could be pivotal for clinical metabolic research (Kasarla et al., 2024).

Components

Contains 10 mg each of TCA cycle metabolite standards packaged individually.

Preparation Note

All components are directly water soluble at ≥ 50 mg/ml.

Kit Components Also Available Separately

Product No.
Description
SDS
  • A2056Acetyl coenzyme A trisodium salt, ≥93% (HPLC), powder 10 mgSDS
  • C7129Citric acid monohydrate, reagent grade, ≥98% (GC/titration) 10 mgSDS
  • F1506Sodium fumarate dibasic, ≥99% 10 mgSDS
  • M1000L-(−)-Malic acid, ≥95% (titration) 10 mgSDS
  • O4126Oxaloacetic acid, ≥97% (HPLC) 10 mgSDS
  • P2256Sodium pyruvate, ReagentPlus®, ≥99% 10 mgSDS
  • S1129Succinyl coenzyme A sodium salt, ≥85% 10 mgSDS
  • S2378Sodium succinate dibasic hexahydrate, ReagentPlus®, ≥99% 10 mgSDS
  • K3752α-Ketoglutaric acid disodium salt hydrate, ≥95% 10 mgSDS
See All (9)

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000385582
0000385582
0000304426
SLCQ9562
SLCQ9560

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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