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D5689

Sigma-Aldrich

DM 235

solid

Synonym(s):

1-Benzoyl-4-propanoylpiperazine, Sunifiram

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About This Item

Empirical Formula (Hill Notation):
C14H18N2O2
CAS Number:
314728-85-3
Molecular Weight:
246.30
MDL number:
MFCD04112755
UNSPSC Code:
12352200
PubChem Substance ID:
24278376

form

solid

color

white

solubility

H2O: 24 mg/mL

SMILES string

CCC(=O)N1CCN(CC1)C(=O)c2ccccc2

InChI

1S/C14H18N2O2/c1-2-13(17)15-8-10-16(11-9-15)14(18)12-6-4-3-5-7-12/h3-7H,2,8-11H2,1H3

InChI key

DGOWDUFJCINDGI-UHFFFAOYSA-N

Biochem/physiol Actions

DM 235 (Sunifiram) is a potent nootropic agent.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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D Manetti et al.
Journal of medicinal chemistry, 43(23), 4499-4507 (2000-11-23)
Several 4-substituted 1-acylpiperazines, obtained by molecular simplification of 4-substituted 1,4-diazabicyclo[4.3.0]nonan-9-ones, have been synthesized and tested in vivo on the mouse passive avoidance test, to evaluate their nootropic activity. The results show that, apparently, an N-acylpiperazine group can mimic the 2-pyrrolidinone

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