02187

Isoorientin

≥98.0% (HPLC)

• Synonym(s): Homoorientin, Luteolin 6-C-β-D-glucoside, Luteolin 6-C-glucoside
• Empirical Formula (Hill Notation): C₂₁H₂₀O₁₁
• CAS Number: 4261-42-1
• Molecular Weight: 448.38
• MDL number: MFCD00017433
• UNSPSC Code: 12352201
• PubChem Substance ID: 329747399

Properties

• assay: ≥98.0% (HPLC)
• SMILES string: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3OC(=CC(=O)c3c2O)c4ccc(O)c(O)c4
• InChI: 1S/C21H20O11/c22-6-14-17(27)19(29)20(30)21(32-14)16-11(26)5-13-15(18(16)28)10(25)4-12(31-13)7-1-2-8(23)9(24)3-7/h1-5,14,17,19-24,26-30H,6H2/t14-,17-,19+,20-,21+/m1/s1
• InChI key: ODBRNZZJSYPIDI-VJXVFPJBSA-N

Description

Biochem/physiol Actions

Luteolin, a common flavonoid, has been shown to inhibit secretion of ET-1 by porcine aortic endothelial cells at a 10 uM concentration. However, the luteolin glycoside compound, luteolin 6-C-glucoside, showed very weak inhibition of ET-1 release and inhibition only occurred at higher concentrations of luteolin 6-C-glucoside.

C-glycosyl flavone with anti-inflammatory, antimicrobial and antioxidant properties. Induces antioxidant response through PI3K singaling.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable