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90526

Supelco

Capsiate

analytical standard

Synonym(s):

(6E)-8-Methyl-6-nonenoic acid (4-hydroxy-3-methoxyphenyl)methyl ester, 4-Hydroxy-3-methoxybenzyl (E)-8-methyl-6-nonenoate, Vanillyl (E)-8-methyl-6-nonenoate

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About This Item

Empirical Formula (Hill Notation):
C18H26O4
CAS Number:
Molecular Weight:
306.40
Beilstein/REAXYS Number:
7933697
UNSPSC Code:
85151701
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-8°C

InChI

1S/C18H26O4/c1-14(2)8-6-4-5-7-9-18(20)22-13-15-10-11-16(19)17(12-15)21-3/h6,8,10-12,14,19H,4-5,7,9,13H2,1-3H3/b8-6+

InChI key

ZICNYIDDNJYKCP-SOFGYWHQSA-N

General description

Capsiate is a capsaicinoid and a non-pungent ingredient of CH-19 sweet pepper. It exhibits anti-obesity and anti-inflammatory properties. Capsiate is reported to be an agonist of capsaicin?binding transient potential vanilloid 1 (TRPV 1) receptors.

Application

Capsiate may be used as an analytical standard for the determination of the analyte in Capsicum species by chromatography techniques.

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hcodes

Hazard Classifications

Aquatic Chronic 4

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Capsiate inhibits ultraviolet B-induced skin inflammation by inhibiting Src family kinases and epidermal growth factor receptor signaling
Lee EJ, et al.
Free Radical Biology & Medicine, 48(9), 1133-1143 (2010)
Capsiate, a non-pungent capsaicin analog, reduces body fat without weight rebound like swimming exercise in mice
Haramizu S, et al.
Biomedical Research, 32(4), 279-284 (2011)
Determination of capsinoids by HPLC-DAD in Capsicum species
Singh S, et al.
Journal of Agricultural and Food Chemistry, 57(9), 3452-3457 (2009)
Quantitation of capsiate and dihydrocapsiate and tentative identification of minor capsinoids in pepper fruits (Capsicum spp.) by HPLC-ESI-MS/MS (QTOF)
Fayos O, et al.
Food Chemistry, 270(9), 264-272 (2019)
Different TRPV 1-mediated brain responses to intragastric infusion of capsaicin and capsiate
Tsurugizawa T, et al.
European Journal of Neurology, 38(11), 3628-3635 (2013)

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