AB9210
Anti-Insulin Degrading Enzyme Antibody
serum, Chemicon®
Synonym(s):
IDE, Insulysin, Insulinase
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat
packaging
antibody small pack of 25 μL
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
rat ... Ins1(24505)
Related Categories
Specificity
Insulin Degrading Enzyme (IDE). It is expected that the antibody will also react with human and mouse due to immunogen sequence homology.
Immunogen
Synthetic peptide from rat IDE.
Application
Anti-Insulin Degrading Enzyme Antibody is an antibody against Insulin Degrading Enzyme for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
Western blotting: 1:10,000-1:20,000. The antibody recognizes a protein of ~110 kDa on rat liver tissue lysate.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Quality
Tested
Physical form
Rabbit serum. Liquid.
Storage and Stability
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Other Notes
Please refer to lot specific datasheet.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Beatriz Merino et al.
Metabolism: clinical and experimental, 113, 154352-154352 (2020-09-12)
The insulin-degrading enzyme (IDE) is a metalloendopeptidase with a high affinity for insulin. Human genetic polymorphisms in Ide have been linked to increased risk for T2DM. In mice, hepatic Ide ablation causes glucose intolerance and insulin resistance when mice are
Carlos M González-Casimiro et al.
Cells, 10(9) (2021-09-29)
Insulin-degrading enzyme (IDE) is a highly conserved and ubiquitously expressed Zn2+-metallopeptidase that regulates hepatic insulin sensitivity, albeit its regulation in response to the fasting-to-postprandial transition is poorly understood. In this work, we studied the regulation of IDE mRNA and protein
Miriam Corraliza-Gómez et al.
Cells, 11(2) (2022-01-22)
The insulin-degrading enzyme (IDE) is a zinc-dependent metalloendopeptidase that belongs to the M16A metalloprotease family. IDE is markedly expressed in the brain, where it is particularly relevant due to its in vitro amyloid beta (Aβ)-degrading activity. The subcellular localization of
Jéssica Taday et al.
Metabolites, 14(3) (2024-03-27)
Astrocytes play fundamental roles in the maintenance of brain homeostasis. The dysfunction of these cells is widely associated with brain disorders, which are often characterized by variations in the astrocyte protein markers GFAP and S100B, in addition to alterations in
Enrique Jurado-Ruiz et al.
Scientific reports, 9(1), 11311-11311 (2019-08-07)
Dietary composition plays an important role in the pathophysiology of type 2 diabetes. Monounsaturated fatty acid consumption has been positively associated with improved insulin sensitivity and β-cell function. We examined whether an extra virgin olive oil (EVOO) high fat diet
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