341573
Fibrinogen, Bovine Plasma
Fibrinogen, CAS 9001-32-5, is a soluble plasma glycoprotein that is synthesized in the hepatic parenchymal cells. Contains mpre than 95% clottable protein.
Synonym(s):
Fibrinogen, Bovine Plasma, Coagulation Factor I
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About This Item
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Quality Level
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
sterile distilled water: soluble
shipped in
wet ice
storage temp.
2-8°C
General description
Do not disturb until the fibrinogen is completely solubilized.
Native fibrinogen from bovine plasma. A plasma glycoprotein synthesized and secreted by hepatic parenchymal cells. Fibrinogen, also known as Coagulation Factor I, is an acute-phase plasma protein found at a concentration of about 300 mg/100 ml. Conversion of soluble fibrinogen to the insoluble clot-forming fibrin is the terminal stage of blood clotting. Clinically, fibrinogen is elevated in pregnancy, after surgical trauma, and myocardial infarction, and is decreased in cases of liver cirrhosis and serum hepatitis.
Native fibrinogen from bovine plasma. An acute phase plasma glycoprotein synthesized and secreted by hepatic parenchymal cells. Contains ≥ 95% clottable proteins.
Warning
Toxicity: Harmful (C)
Physical form
Lyophilized from 20 mM sodium citrate-HCl, pH 7.4.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C) for long term storage or store at room temperature (20°C) for short term storage. Do not store solutions on ice; precipitation will occur. Stock solutions are stable for up to 4 h at 20°C or for up to 6 months at -20°C.
Solutions used to reconstitute fibrinogen should first be brought to 37°C. Once at 37°C, the solution can be added to the fibrinogen and this mixture should remain at 37°C until the fibrinogen is completely solubilized.
Analysis Note
homogeneous by SDS-PAGE.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
Certificates of Analysis (COA)
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