Y0002160

Donepezil hydrochloride

CRS, European Pharmacopoeia (EP) Reference Standard

• Synonym(s): 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride, E2020
• Empirical Formula (Hill Notation): C₂₄H₂₉NO₃ · HCl
• CAS Number: 120011-70-3
• Molecular Weight: 415.95
• MDL number: MFCD00881312
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• API family: donepezil
• manufacturer/tradename: EDQM
• SMILES string: O=C1C(CC2CCN(CC3=CC=CC=C3)CC2)CC4=CC(OC)=C(OC)C=C41.[H]Cl
• InChI: 1S/C24H29NO3.ClH.H2O/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H;1H2
• InChI key: HLJIZAKUNCTCQX-UHFFFAOYSA-N
• Gene Information: human ... ACHE(43)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Donepezil hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Donepezil monohydrochloride monohydrate is a centrally acting reversible acetylcholinesterase inhibitor.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H300,H319
• pcodes: P264 - P270 - P280 - P301 + P310 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Acute Tox. 2 Oral - Eye Irrit. 2
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable