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SML3374

Sigma-Aldrich

Eurycomanone

≥95% (HPLC)

Synonym(s):

(1β,11β,12α,15β)-11,20-Epoxy-1,11,12,14,15-pentahydroxypicrasa-3,13(21)-diene-2,16-dione, NSC 339187, Pasakbumin A

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About This Item

Empirical Formula (Hill Notation):
C20H24O9
CAS Number:
84633-29-4
Molecular Weight:
408.40
MDL number:
MFCD31726288
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

assay

≥95% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

InChI

1S/C20H24O9/c1-7-4-10(21)13(23)17(3)9(7)5-11-18-6-28-20(27,16(17)18)12(22)8(2)19(18,26)14(24)15(25)29-11/h4,9,11-14,16,22-24,26-27H,2,5-6H2,1,3H3/t9-,11+,12+,13+,14-,16+,17+,18+,19-,20-/m0/s1

InChI key

UCUWZJWAQQRCOR-OKNZMGBLSA-N

Biochem/physiol Actions

Eurycomanone is a main ingredient of commonly consumed herbal preparation Eurycoma longifolia Jack that exhibits antimalarial, antipyretic, aphrodisiac, and cytotoxic activities. Eurycomanone improves spermatogenesis by inhibition of aromatase conversion of testosterone to estrogen, and phosphodiesterase inhibition.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Norzahirah Ahmad et al.
Pharmaceutics, 10(3) (2018-07-13)
Eurycoma longifolia is one of the commonly consumed herbal preparations and its major chemical compound, eurycomanone, has been described to have antimalarial, antipyretic, aphrodisiac, and cytotoxic activities. Today, the consumption of E. longifolia is popular through the incorporation of its
Putri Ayu Jayusman et al.
Nutrients, 10(7) (2018-06-24)
Male osteoporosis is associated with higher rates of disability and mortality. Hence the search for suitable intervention and treatment to prevent the degeneration of skeletal health in men is necessary. Eurycoma longifolia (EL), a traditional plant with aphrodisiac potential may
Bin-Seng Low et al.
Journal of ethnopharmacology, 149(1), 201-207 (2013-07-03)
Eurycoma longifolia Jack (Simaroubaceae family), known locally as 'Tongkat Ali' by the ethnic population, is popularly taken as a traditional remedy to improve the male libido, sexual prowess and fertility. Presently, many tea, coffee and carbonated beverages, pre-mixed with the

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