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SML3276

Sigma-Aldrich

Apelin-17 trifluoroacetate salt

≥95% (HPLC)

Synonym(s):

Apelin 17 trifluoroacetate salt, K17F trifluoroacetate salt, L-Lysyl-L-phenylalanyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine trifluoroacetate salt, Lys-Phe-Arg-Arg-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe

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5 MG
$80.18
25 MG
$341.00

$80.18

List Price$84.40
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5 MG
$80.18
25 MG
$341.00

About This Item

UNSPSC Code:
12352202
NACRES:
NA.77
assay:
≥95% (HPLC)
form:
powder

$80.18

List Price$84.40
Web-Only Promotion

Available to ship onApril 23, 2025Details

Quality Level

100

assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

white to off-white

storage temp.

−20°C

Related Categories

Biochem/physiol Actions

Apelin-17 (K17F) is a potent and selective endogenous agonist of apelin receptor (apelin-R). Apelin-17 has 16 times higher affinity for apelin-R than apelin-13 (pE13F) (Ki = 0.05 versus 0.8 nM).
potent and selective endogenous agonist of apelin receptor (apelin-R)

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000184642
0000184641
0000179960

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Wang Wang et al.
Hypertension (Dallas, Tex. : 1979), 68(2), 365-377 (2016-05-25)
Apelin peptides mediate beneficial effects on the cardiovascular system and are being targeted as potential new drugs. However, apelin peptides have extremely short biological half-lives, and improved understanding of apelin peptide metabolism may lead to the discovery of biologically stable
Adrien Flahault et al.
Nature communications, 12(1), 305-305 (2021-01-14)
Apelin and arginine-vasopressin (AVP) are conversely regulated by osmotic stimuli. We therefore hypothesized that activating the apelin receptor (apelin-R) with LIT01-196, a metabolically stable apelin-17 analog, may be beneficial for treating the Syndrome of Inappropriate Antidiuresis, in which AVP hypersecretion

Questions

  1. Quel est le poids moléculaire de l'apelin17 ?

    1 answer

    1. The molecular weight of this product has not been determined. However, PubChem lists a molecular weight of 2138.6 g/mol. Please see the link below to reivew the PubChem profile:
      https://pubchem.ncbi.nlm.nih.gov/compound/16130452

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