SML3173

Gatifloxacin sesquihydrate

≥98% (HPLC)

• Synonym(s): Gatifloxacin sesquihydrate, (±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid sesquihydrate, 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid sesquihydrate
• Empirical Formula (Hill Notation): C₁₉H₂₂FN₃O₄ · 1.5H₂O
• CAS Number: 180200-66-2
• Molecular Weight: 402.42
• Beilstein/REAXYS Number: 14390028
• MDL number: MFCD22373645
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (Warmed)
• Storage temp.: 2-8°C
• SMILES string: O=C(O)C1=CN(C2CC2)C3=C(OC)C(N4CCNC(C)C4)=C(F)C=C3C1=O.O=C(O)C5=CN(C6CC6)C7=C(OC)C(N8CCNC(C)C8)=C(F)C=C7C5=O.O.O.O
• InChI: 1S/2C19H22FN3O4.3H2O/c2*1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26;;;/h2*7,9-11,21H,3-6,8H2,1-2H3,(H,25,26);3*1H2
• Inchi Key: RMJMZKDEVNTXHE-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Gatifloxacin sesquihydrateis an oral fluoroquinolone broad spectrum antibiotic, inhibitor of bacterial enzymes DNA gyrase and topoisomerase IV, with improved gram-positive and anaerobe coverage. Gatifloxacin is reported to be useful to treat ocular infection and does not appear to cause phototoxic effects.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable