SML1141

Solasodine

≥95% (HPLC)

• Synonym(s): (-)-Solasodine, (3β,22α,25R)-Spirosol-5-en-3-ol, NSC 178260, NSC 179187, Purapuridine, Solancarpidine, Solasod-5-en-3β-ol, Solasod-5-en-3β-ol (7CI,8CI), Solasodin
• Empirical Formula (Hill Notation): C₂₇H₄₃NO₂
• CAS Number: 126-17-0
• Molecular Weight: 413.64
• EC Number: 204-774-2
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• assay: ≥95% (HPLC)
• form: powder
• optical activity: [α]/D -88 to -98°, c = 0.2 in methanol
• color: white to beige
• solubility: DMSO: 0.5 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: C[C@@H]1[C@]2(NC[C@H](C)CC2)O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC=C6C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]31[H]
• InChI: 1S/C27H43NO2/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28-29H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1
• InChI key: KWVISVAMQJWJSZ-VKROHFNGSA-N

Description

Application

Solasodine has been used in viability assays.

Biochem/physiol Actions

Solasodine is a neuroprotective antioxidant glycoalkaloid of Solanum species. Solasodine increases superoxide dismutase (SOD), catalase (CAT),and glutathione (GSH) levels, while reducing lipid peroxidation (LPO) and nitric oxide (NO) levels in the brains of ischemia/reperfusion (I/R)-injury model in rats. Also, Solasonine displayed multiple activities including, anti-cancer and leishmanicidal activities.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable