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S8540

Sigma-Aldrich

Ser-Gly-Gln-Ser-Trp-Arg-Pro-Gln-Gly-Arg-Phe-NH2

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C57H85N21O15
CAS Number:
127122-98-9
Molecular Weight:
1304.42
MDL number:
MFCD00080357
UNSPSC Code:
12352200
PubChem Substance ID:
24899799

assay

≥97% (HPLC)

UniProt accession no.

P01303

storage temp.

−20°C

SMILES string

NC(CO)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NC(CO)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCCNC(N)=N)C(=O)N3CCCC3C(=O)NC(CCC(N)=O)C(=O)NCC(=O)NC(CCCNC(N)=N)C(=O)NC(Cc4ccccc4)C(N)=O

Gene Information

human ... NPY(4852)

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Biochem/physiol Actions

Cardioexcitatory peptide from the African giant snail

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
047H0008
024H01512
024H01511
047H00081

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S Pedder et al.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 103(3), 441-451 (1992-11-01)
1. Intracellular recordings were made from identified neurones in the suboesophageal ganglia of Helix aspersa. Seven neuropeptides were tested for activity and their actions compared with acetylcholine and FMRFamide. 2. Three peptides isolated from nematodes, AF-1, AF-2 and PAN-1 had
M Fujimoto et al.
Biochemical and biophysical research communications, 242(2), 436-440 (1998-02-03)
A novel bioactive peptide with the C-terminal RFamide was isolated from the brain of the Japanese crucian carp, Carassius auratus langsdorfii, by using the intestine of the fish as the bioassay system. The primary structure of the peptide was determined
K Fujimoto et al.
Biochemical and biophysical research communications, 167(2), 777-783 (1990-03-16)
An undecapeptide which potentiates the beat of the ventricle in the African giant snail, Achatina fulica Ferussac, was purified from the atria of the snail. Its primary structure was determined to be H-Ser-Gly-Gln-Ser-Trp-Arg-Pro-Gln-Gly-Arg-Phe-NH2. This peptide was found to have excitatory
C Baud et al.
Cellular and molecular neurobiology, 18(4), 413-424 (1998-06-10)
1. We report the isolation of a peptide from the brain of the snail Helix aspersa by radioimmunoassay using an antisomatostatin. 2. The sequencing of an immunopositive fraction showed the presence of a new tridecapeptide, termed Helix cardioinhibitory peptide (HCIP)

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