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S1650

Sigma-Aldrich

Seleno-DL-cystine

>98% (TLC), suitable for HPLC

Synonym(s):

3,3′-diselenobis- alanine,

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About This Item

Empirical Formula (Hill Notation):
C6H12N2O4Se2
CAS Number:
2897-21-4
Molecular Weight:
334.09
MDL number:
MFCD00055925
UNSPSC Code:
12352209
PubChem Substance ID:
24899489
NACRES:
NA.26

Product Name

Seleno-DL-cystine, powder

assay

>98% (TLC)

Quality Level

200

form

powder

technique(s)

HPLC: suitable

mp

222 °C

storage temp.

−20°C

SMILES string

NC(C[Se][Se]CC(N)C(O)=O)C(O)=O

InChI

1S/C6H12N2O4Se2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)

InChI key

JULROCUWKLNBSN-UHFFFAOYSA-N

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Related Categories

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
SLCF7424
SLBX1264
SLBW7166
SLBS2849V
MKBR6191V

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Pierre Burguière et al.
Journal of bacteriology, 186(15), 4875-4884 (2004-07-21)
The symporter YhcL and two ATP binding cassette transporters, YtmJKLMN and YckKJI, were shown to mediate L-cystine uptake in Bacillus subtilis. A triple DeltayhcL DeltaytmJKLMN DeltayckK mutant was unable to grow in the presence of L-cystine and to take up
Rui Gusmão et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 17(2), 321-329 (2011-10-22)
Selenium-containing compounds play an important role in antioxidant defense systems, binding to toxic metals, preventing their uptake into cells, and thus protecting cells from metal-induced formation of reactive oxygen species. Here, we present a proposal for a relatively new method
Eric Olm et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(27), 11400-11405 (2009-06-25)
The selenium salt selenite (SeO(3)(2-)) is cytotoxic in low to moderate concentrations, with a remarkable specificity for cancer cells resistant to conventional chemotherapy. Our data show that selenium uptake and accumulation, rather than intracellular events, are crucial to the specific
F Moreno et al.
The Analyst, 135(10), 2700-2705 (2010-08-21)
The simultaneous speciation of elements is of great concern, especially in the study of the interactions of species in living organisms. Here we report a method based on the coupling of HPLC-ICP-MS that is capable of separating and analyzing different
Tianfeng Chen et al.
The international journal of biochemistry & cell biology, 41(3), 666-676 (2008-08-23)
The role of selenium as potential cancer chemopreventive and chemotherapeutic agents has been supported by epidemiological, preclinical and clinical studies. Although cell apoptosis has been evidenced as a critical mechanism mediating the anticancer activity of selenium, the underlying molecular mechanisms
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