M5199

Meldonium dihydrate

≥98% (HPLC), powder

• Synonym(s): MET 88, Quaterin
• Empirical Formula (Hill Notation): C₆H₁₄N₂O₂ · 2H₂O
• CAS Number: 86426-17-7
• Molecular Weight: 182.22
• MDL number: MFCD00876389
• UNSPSC Code: 12352200
• PubChem Substance ID: 329818003
• NACRES: NA.77

Properties

• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to off-white
• solubility: H₂O: >40 mg/mL
• storage temp.: 2-8°C
• SMILES string: C[N+](C)(C)NCCC([O-])=O
• InChI: 1S/C6H14N2O2/c1-8(2,3)7-5-4-6(9)10/h7H,4-5H2,1-3H3
• InChI key: PVBQYTCFVWZSJK-UHFFFAOYSA-N

Description

Application

Meldonium dihydrate has been used as an anti-ischemic agent to evaluate its protective effects on Ischemia-reperfusion (I/R) in chick embryos.

Biochem/physiol Actions

Meldonium exhibits anti-ischemic activity and shows therapeutic effects against cerebral and cardiac ischemic disorders.

Meldonium is an Inhibitor of γ-butyrobetaine hydroxylase (BBOX) a key enzyme in the synthesis of carnitine.

Meldonium is an inhibitor of γ-butyrobetaine hydroxylase (BBOX).

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable