L4646

Lipids Cholesterol Rich from adult bovine serum

liquid, sterile-filtered, BioReagent, suitable for cell culture, suitable for insect cell culture

• Synonym(s): Bovine Serum Lipids, Cholesterol Rich Lipids, Lipids from Bovine
• UNSPSC Code: 12352211
• NACRES: NA.75

Properties

• sterility: sterile-filtered
• Quality Level: 200
• product line: BioReagent
• form: liquid
• composition: Cholesterol, 9.0-11.0 g/L ; Protein, 15.0-25.0 g/L
• technique(s): cell culture | insect: suitable; cell culture | mammalian: suitable
• impurities: Adventitious viral agents, none detected (9 CFR; 113.53); IgG, none detected (RID); Microbial content, none detected (USP XXII); Mycoplasma, none detected (Barile method); ≤6.0 EU/mg cholesterol endotoxin
• storage temp.: 2-8°C

Description

General description

Cholesterol is a lipid molecule,[1] found integrated to the cell membrane.[2]

Application

Lipids Cholesterol Rich from adult bovine serum has been used as one of the lipid component to generate erythroblasts ex vivo.[3] It has also been used as a standard to determine muscle cholesterol level, spectrophotometrically.[4][5]

Biochem/physiol Actions

Cholesterol significantly affects the property of phospholipid membrane such as fluidity and membrane protein function.[6] It exhibits a condensing effect towards phospholipids.[1] Cholesterol-phospholipid interaction influences physiological properties of a lipid bilayer.[7] Cholesterol serves as a precursor of bile acids, steroid hormones and vitamin D. Uncontrolled level of plasma cholesterol might lead to the risk of cardiovascular disorder.[8]

Other Notes

Aqueous lipoprotein solution

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable