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H9262

Sigma-Aldrich

(Hydroxypropyl)methyl cellulose

viscosity 80-120 cP, 2 % in H2O(20 °C)(lit.)

Synonym(s):

2-Hydroxypropyl methyl cellulose ether

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.56

form

powder

mol wt

~26 kDa

color

beige

viscosity

80-120 cP, 2 % in H2O(20 °C)(lit.)

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Application

(Hydroxypropyl)methyl cellulose acts as a thickener for aqueous and non-aqueous systems, is a water retention aid and steric stabilizer, and clear films with grease resistance. (Hydroxypropyl)methyl cellulose has been used to study mucoadhesion in the design of drug delivery systems to prolong intestinal residence time and has also been used to study the enhancement of dissolution rate of poorly water soluble drugs.
Thickener for aqueous and non-aqueous systems, clear films with grease resistance, binders, lubricants, steric stabilizer and water retention aid.

Features and Benefits

Dissolves in water, undergoes reversible gelation upon heating, non-ionic, does not complex with ionic species and is surface active and enzyme resistant. Solutions are pseudoplastic.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Deirdre M D'Arcy et al.
AAPS PharmSciTech, 20(2), 47-47 (2019-01-09)
Viscosity, influenced by medium composition, will affect the hydrodynamics of a dissolution system. Dissolution simulation methods are valuable tools to explore mechanistic dissolution effects, with an understanding of limitations of any simulation method essential to its appropriate use. The aims
Lucas Sievens-Figueroa et al.
International journal of pharmaceutics, 423(2), 496-508 (2011-12-20)
The design and feasibility of a simple process of incorporating stable nanoparticles into edible polymer films is demonstrated with the goal of enhancing the dissolution rate of poorly water soluble drugs. Nanosuspensions produced from wet stirred media milling (WSMM) were
A Akbarian et al.
Poultry science, 93(8), 1930-1941 (2014-06-17)
Heat stress in poultry is a serious problem in many countries and has been associated with oxidative stress. Hence, nutritional interventions with antioxidants might be beneficial. Therefore, the effects of dietary Curcuma xanthorrhiza (CX) and Origanum compactum (OC) essential oils
Michelle Lay Teng Ang et al.
Infection and immunity, 82(5), 1850-1859 (2014-02-26)
Tuberculosis remains a major worldwide epidemic because of its sole etiological agent, Mycobacterium tuberculosis. Ethionamide (ETH) is one of the major antitubercular drugs used to treat infections with multidrug-resistant M. tuberculosis strains. ETH is a prodrug that requires activation within
Eun-Ji Won et al.
Aquatic toxicology (Amsterdam, Netherlands), 150, 17-26 (2014-03-19)
Accidental nuclear radioisotope release into the ocean from nuclear power plants is of concern due to ecological and health risks. In this study, we used the marine copepod Paracyclopina nana to examine the effects of radioisotopes on marine organisms upon

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