D4506

4-(Dimethylamino)cinnamaldehyde

>97.5% purity (HPLC), powder

• Synonym(s): DMAC, DMACA
• Linear Formula: (CH₃)₂NC₆H₄CH=CHCHO
• CAS Number: 6203-18-5
• Molecular Weight: 175.23
• Beilstein/REAXYS Number: 972369
• EC Number: 228-267-0
• MDL number: MFCD00007002
• UNSPSC Code: 12171500
• PubChem Substance ID: 24893878
• NACRES: NA.47

Properties

• Product Name: 4-(Dimethylamino)cinnamaldehyde, chromogenic reagent for indoles and flavanols
• Quality Level: 200
• assay: ≥98% (HPLC)
• form: powder
• technique(s): titration: suitable
• color: yellow to very dark yellow
• mp: 138-140 °C (lit.)
• solubility: chloroform/ethanol (1:1): 50 mg/mL
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: −20°C
• SMILES string: CN(C)c1ccc(\C=C\C=O)cc1
• InChI: 1S/C11H13NO/c1-12(2)11-7-5-10(6-8-11)4-3-9-13/h3-9H,1-2H3/b4-3+
• InChI key: RUKJCCIJLIMGEP-ONEGZZNKSA-N

Description

Application

• 4-(Dimethylamino)cinnamaldehyde (DMAC) has been used in the serine protease inhibition assay.[1]
• It has been used for the detection of (epi)-flavan-3-ols and proanthocyanidin polymers in Brassica napus seeds.[2]
• It has been used for the determination of phenolic compounds in leaf samples.[3]
• It has been used for the staining of flavan-3-ols in plant samples.[4]

Biochem/physiol Actions

Reagent for assay of indole product of apotryptophanase and tryptophanase.[5] DMAC produces colored adducts with flavanols for subsequent HPLC.[6][7] It has been used in a chromogenic method for quantifying proanthocyandines in cranberry powder.[8][9]

Safety Information

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H315,H319,H335,H411
• pcodes: P273 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves