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D4266

Sigma-Aldrich

3-(Decyldimethylammonio)­propane­sulfonate inner salt

zwitterionic detergent

Synonym(s):

Caprylyl sulfobetaine, SB3-10

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About This Item

Linear Formula:
CH3(CH2)9N+(CH3)2CH2CH2CH2SO3-
CAS Number:
15163-36-7
Molecular Weight:
307.49
Beilstein/REAXYS Number:
3967284
MDL number:
MFCD00036908
UNSPSC Code:
12161900
PubChem Substance ID:
24893849
NACRES:
NA.25

assay

≥98.0% (TLC)

form

powder

mol wt

micellar avg mol wt 12,600

aggregation number

41

technique(s)

enzyme immunoassay: suitable
protein purification: suitable
protein quantification: suitable

conductivity

<20 μmho per cm at 24 °C (0.1 M aqueous solution)

CMC

25-40 mM (20-25°C)

SMILES string

CCCCCCCCCC[N+](C)(C)CCCS([O-])(=O)=O

InChI

1S/C15H33NO3S/c1-4-5-6-7-8-9-10-11-13-16(2,3)14-12-15-20(17,18)19/h4-15H2,1-3H3

InChI key

WKALLSVICJPZTM-UHFFFAOYSA-N

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General description

3-(Decyldimethylammonio)­propane­sulfonate inner salt, a zwitterionic surfactant, is a sulfobetaine. Sulfobetaines contain a positively charged quaternary ammonium group and a negatively charged sulfonic group.

Application

3-(Decyldimethylammonio)­propane­sulfonate inner salt was used:
  • In a study to demonstrate a polyurethane chip that electrostatically binds to immunoglobulin G (IgG).
  • In a study to describe a method for isolating a high yield of Arabidopsis chloroplasts.
  • Solubilization of oleosins.
Zwitterionic detergent used for protein solubilization.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Solubilization conditions for hydrophobic membrane protein, oleosin, in soybeans
Kim, H., et al.
Biotechnology and Bioprocess Engineering: BBE, 12, 542-542 (2007)
Effects of long-chains of zwitterionic micelles on binding constants of triflusal and acetylsalicylic acid.
Ferrit M, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 345(1), 26-30 (2009)
Synthesis and surface-active properties of sulfobetaine-type zwitterionic gemini surfactants.
Yoshimura T, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 273(1), 208-212 (2006)
Kenji Murakami et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(13), 4816-4821 (2012-03-14)
General transcription factor TFIIH, previously described as a 10-subunit complex, is essential for transcription and DNA repair. An eleventh subunit now identified, termed Tfb6, exhibits 45% sequence similarity to human nuclear mRNA export factor 5. Tfb6 dissociates from TFIIH as
W Schulz et al.
Journal of steroid biochemistry, 32(4), 581-590 (1989-04-01)
11 beta-hydroxysteroid dehydrogenase (11-HSD, EC 1.1.1.146) from rat renal cortex microsomes was solubilized using several detergents, the most effective being Zwittergent 3-10 and Triton X-100. The activity ratio oxidation/reduction of the reversible reaction corticosterone in equilibrium 11-dehydrocoticosterone varied depending on
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