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C4361

Sigma-Aldrich

Bovine Collagen Type I

from bovine skin, liquid, 1 mg/mL, FITC Conjugated, used for gel analysis, cell seeding, and collagenase assays

Synonym(s):

Collagen from bovine skin

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.32

product name

Collagen Type I−FITC Conjugate from bovine skin, ~1 mg/mL, solution

biological source

bovine skin

Quality Level

form

solution

concentration

~1 mg/mL

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

General description

Type I collagen is the major collagen of tendon and bone, but it is widely distributed in other tissues, such as skin, cornea, tooth dentin, heart valve, lung, liver, fascia and scar tissue.

Application

Collagen Type I-FITC Conjugate from bovine skin has been used in collagen I gel deformation analysis. It has also been used to coat silicone elastic membranes for seeding cells for various experimental studies. It can also be used as a substrate for assaying mammalian collagenase activity in cell culture.

Biochem/physiol Actions

Collagen type I offers mechanical stability, strength and toughness to a range of tissues from tendons and ligaments, to skin, cornea, bone and dentin.

Physical form

Supplied in 0.01 M acetic acid.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles


Certificates of Analysis (COA)

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F Nelson et al.
The Journal of clinical investigation, 102(12), 2115-2125 (1998-12-17)
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5-methoxy tryptophan (5-MTP) is an anti-fibrotic metabolite made by fibroblasts and epithelial cells, present in a micromolar concentrations in human blood, and is associated with the progression of fibrotic kidney disease, but the mechanism is unclear. Here, we show by
Processing of collagen-based biomaterials and the resulting materials properties
Meyer M, et al.
BioMedical Engineering OnLine, 18 (2019)

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