B7639

(+)-Biotin hydrazide

≥97% (TLC), powder

• Empirical Formula (Hill Notation): C₁₀H₁₈N₄O₂S
• CAS Number: 66640-86-6
• Molecular Weight: 258.34
• Beilstein/REAXYS Number: 28347
• MDL number: MFCD00078532
• UNSPSC Code: 12352203
• PubChem Substance ID: 24892012
• NACRES: NA.46

Properties

• assay: ≥97% (TLC)
• form: powder
• solubility: DMSO: ≤20 mg/mL
• storage temp.: 2-8°C
• SMILES string: [H][C@]12CS[C@@H](CCCCC(=O)NN)[C@@]1([H])NC(=O)N2
• InChI: 1S/C10H18N4O2S/c11-14-8(15)4-2-1-3-7-9-6(5-17-7)12-10(16)13-9/h6-7,9H,1-5,11H2,(H,14,15)(H2,12,13,16)/t6-,7-,9-/m0/s1
• InChI key: KOZWHQPRAOJMBN-ZKWXMUAHSA-N

Description

General description

Biotin hydrazide is a biotinylation reagent used to biotinylate glycoproteins with their sugar moieties[1]. Biotin hydrazide can be used to prepare biotin-conjugated alginate[2]. It can also be used for covalent attachment to PAAc via carbodi-imide cross linking[3].

Application

(+)-Biotin hydrazide has been used:

• the modification of alginate[4]
• for the labelling of mitochondrial proteins from non-muscle tissues[5]
• as a component of glycoprotein staining solution[6]
• in periodic acid-biotin-hydrazide (PABH) assay for mucins[7]
• for labeling surface functional groups, biologically active molecules such as antibodies, lectins, sugars, nucleic acids or molecules with free carboxylic or keto groups.
• for coupling to glycoproteins through the carbohydrate by hydrazone formation

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)