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F1635

SAFC

Formaldehyde solution

contains 10-15% methanol as stabilizer, 37 wt. % in H2O

Synonym(s):

Formalin

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25 ML
$39.30
500 ML
$55.60
4 L
$143.00

$39.30

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25 ML
$39.30
500 ML
$55.60
4 L
$143.00

About This Item

Linear Formula:
HCHO
CAS Number:
50-00-0
Molecular Weight:
30.03
Beilstein/REAXYS Number:
1209228
MDL number:
MFCD00003274
UNSPSC Code:
12352114
PubChem Substance ID:
329799685
NACRES:
NA.21
technique(s):
tissue processing: suitable
bp:
97 °C
vapor pressure:
52 mmHg ( 37 °C)

$39.30

In StockDetails

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vapor density

1.03 (vs air)

Quality Level

200

vapor pressure

52 mmHg ( 37 °C)

form

liquid

autoignition temp.

572 °F

contains

10-15% methanol as stabilizer

concentration

37 wt. % in H2O
37-38%

technique(s)

tissue processing: suitable

impurities

≤0.03% free acid (as HCOOH)

color

APHA: ≤10

pH

2.8-4.0

bp

97 °C

mp

-15 °C

density

1.09 g/mL at 25 °C (lit.)

SMILES string

[H]C([H])=O

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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General description

This product is 37wt% solution of formaldehyde in water. It contains 10-15% methanol as stabilizer.

Application

Formaldehyde solution has been used to prepare formaldehyde fixation/permeabilization solution that is employed to fix tissue samples.[1]

Biochem/physiol Actions

Induces tumors in the nasal epithelium of rats, and is suspected to be a human carcinogen. Potent mutagen.

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3

target_organs

Eyes,Central nervous system, Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

133.0 °F - closed cup

flash_point_c

56.11 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV6719
MKCW6678
MKCV4425
MKCT1780
MKCS2465

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Omer Barkai et al.
Pain, 160(6), 1281-1296 (2019-04-02)
Endogenous inflammatory mediators contribute to the pathogenesis of pain by acting on nociceptors, specialized sensory neurons that detect noxious stimuli. Here, we describe a new factor mediating inflammatory pain. We show that platelet-derived growth factor (PDGF)-BB applied in vitro causes
Christopher Bruhn et al.
Genomics, proteomics & bioinformatics, 12(6), 255-265 (2014-12-03)
Cell cycle progression is coordinated with metabolism, signaling and other complex cellular functions. The investigation of cellular processes in a cell cycle stage-dependent manner is often the subject of modern molecular and cell biological research. Cell cycle synchronization and immunostaining
Cindy S Ma et al.
The Journal of experimental medicine, 205(7), 1551-1557 (2008-07-02)
Hyper-immunoglobulin E syndrome (HIES) is a primary immune deficiency characterized by abnormal and devastating susceptibility to a narrow spectrum of infections, most commonly Staphylococcus aureus and Candida albicans. Recent investigations have identified mutations in STAT3 in the majority of HIES
Arpeeta Sharma et al.
Diabetes, 64(11), 3937-3950 (2015-06-28)
Patients with diabetes have an increased risk of developing atherosclerosis. Endothelial dysfunction, characterized by the lowered bioavailability of endothelial NO synthase (eNOS)-derived NO, is a critical inducer of atherosclerosis. However, the protective aspect of eNOS in diabetes-associated atherosclerosis remains controversial
G R Moore et al.
Neurology, 55(10), 1506-1510 (2000-11-30)
To determine the pathologic basis of areas not exhibiting signal of the short-T2 component of the T2 relaxation distribution in MS, as studied in formalin-fixed brain. A myelin-specific MRI signal would be of great importance in assessing demyelination in patients
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Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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