Skip to Content
MilliporeSigma
All Photos(3)

Key Documents

View All Documentation

443778

Sigma-Aldrich

NMP

ACS reagent, ≥99.0%

Synonym(s):

1-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidone, NMP

Sign Into View Organizational & Contract Pricing

Select a Size

500 ML
$101.00
1 L
$155.00
2.5 L
$259.00
18 L
$1,180.00

$101.00

In StockDetails

Request a Bulk Order
All Photos(3)

Select a Size

Change View
500 ML
$101.00
1 L
$155.00
2.5 L
$259.00
18 L
$1,180.00

About This Item

Empirical Formula (Hill Notation):
C5H9NO
CAS Number:
872-50-4
Molecular Weight:
99.13
Beilstein/REAXYS Number:
106420
EC Number:
212-828-1
MDL number:
MFCD00003193
UNSPSC Code:
12352005
PubChem Substance ID:
329756501
NACRES:
NA.21
grade:
ACS reagent
assay:
≥99.0%
bp:
202 °C (lit.)
81-82 °C/10 mmHg (lit.)
vapor pressure:
0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

$101.00

In StockDetails

Request a Bulk Order

Product Name

1-Methyl-2-pyrrolidinone, ACS reagent, ≥99.0%

grade

ACS reagent

Quality Level

200

vapor density

3.4 (vs air)

vapor pressure

0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

assay

≥99.0%

form

liquid

autoignition temp.

518 °F

expl. lim.

9.5 %

impurities

≤0.01% Free amines (as CH3NH2)
≤0.05% water

color

APHA: ≤50

refractive index

n20/D 1.47 (lit.)

pH

7.7-10.0 (20 °C, 100 g/L)

bp

202 °C (lit.)
81-82 °C/10 mmHg (lit.)

mp

−24 °C (lit.)

solubility

acetone: miscible(lit.)
alcohol: miscible(lit.)
benzene: miscible(lit.)
chloroform: miscible(lit.)
ethyl acetate: miscible(lit.)
water: miscible(lit.)

density

1.028 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤1 ppm

SMILES string

CN1CCCC1=O

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

InChI key

SECXISVLQFMRJM-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

1-Methyl-2-pyrrolidinone may be used as:
  • An alternative eluent to THF in the size exclusion chromatography (SEC) based resolution of coal-derived liquids.[1]
  • Reaction medium to prepare 2-aryl and 2-alkyl benzothiazoles.[2]
  • A solvent in the ultrasonic preparation of metal organic framework (MOF-177) crystals.[3]
It may be used to synthesize single-phase chalcopyrite CuInSe2 nanocrystals[4] and potassium 3-methyl-2-oxo-pyrrolidinenitronate.[5]

Packaging

View returnable container options.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 1

flash_point_f

195.8 °F - Pensky-Martens closed cup

flash_point_c

91 °C - Pensky-Martens closed cup

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SHBS5045
SHBR8953
SHBR5574
SHBR5572
SHBS3124

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

1-Methyl-2-pyrrolidone Meets ACS Specifications GR ACS

Supelco

MX1395

1-Methyl-2-pyrrolidone

1-Methyl-2-pyrrolidone for Peptide Synthesis

Supelco

1.00574

1-Methyl-2-pyrrolidone

A Green and Air Pressure Solution Synthesis of CuInSe2 Nanocrystals Using 1-methyl-2-Pyrrolidinone as Hot Solvent.
Wang W, et al.
Journal of the American Ceramic Society. American Ceramic Society, 94(8), 2571-2577 (2011)
Alkyl nitrate nitration of active methylene-compounds. 15. Nitration of 1-methyl-4-piperidone, 1-methyl-2-pyrrolidinone and 1,3-dimethyl-2-pyrrolidinone.
Feuer H, et al.
Journal of Heterocyclic Chemistry, 16(3), 481-485 (1979)
Aneuploidy induction in Saccharomyces cerevisiae by two solvent compounds, 1-methyl-2-pyrrolidinone and 2-pyrrolidinone.
Mayer VW, et al.
Environmental and Molecular Mutagenesis, 11(1), 31-40 (1988)
Solubility limitations in the determination of molecular mass distributions of coal liquefaction and hydrocracking products: 1-methyl-2-pyrrolidinone as mobile phase in size exclusion chromatography.
Herod AA, et al.
Energy and Fuels, 10(3), 743-750 (1996)
Da-Won Jung et al.
Dalton transactions (Cambridge, England : 2003), 39(11), 2883-2887 (2010-03-05)
High quality MOF-177 crystals in the size range of 5-20 microm were successfully synthesized via a sonochemical route in a substantially reduced synthesis time (40 min) in the presence of low-cost NMP (1-methyl-2-pyrrolidone) as a solvent. Microwave heating in NMP
View All Related Papers

Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service